[HTML][HTML] Cannabidiol for the treatment of brain disorders: therapeutic potential and routes of administration
The use of cannabidiol (CBD) for treating brain disorders has gained increasing interest.
While the mechanism of action of CBD in these conditions is still under investigation, CBD …
While the mechanism of action of CBD in these conditions is still under investigation, CBD …
Nanoformulations as a strategy to overcome the delivery limitations of cannabinoids
Medical cannabis has received significant interest in recent years due to its promising
benefits in the management of pain, anxiety, depression and neurological and movement …
benefits in the management of pain, anxiety, depression and neurological and movement …
[HTML][HTML] Current challenges and opportunities for improved cannabidiol solubility
Cannabidiol (CBD), derived from the cannabis plant, has gained significant attention due to
its potential therapeutic benefits. However, one of the challenges associated with CBD …
its potential therapeutic benefits. However, one of the challenges associated with CBD …
Therapeutic targeting of the tumor microenvironments with cannabinoids and their analogs: Update on clinical trials
Cancer is a major global public health concern that affects both industrialized and
developing nations. Current cancer chemotherapeutic options are limited by side effects, but …
developing nations. Current cancer chemotherapeutic options are limited by side effects, but …
The dose-dependent effect of a stabilized cannabidiol nanoemulsion on ocular surface inflammation and intraocular pressure
Cannabidiol (CBD) is a phytocannabinoid that has a great clinical therapeutic potential. Few
studies have been published on its efficacy in ocular inflammations while its impact on …
studies have been published on its efficacy in ocular inflammations while its impact on …
An update of nano-based drug delivery systems for cannabinoids: Biopharmaceutical aspects & therapeutic applications
Nanotechnology has been widely used to improve stability, efficacy, release control and
biopharmaceutical aspects of natural and synthetic cannabinoids. In this review, the main …
biopharmaceutical aspects of natural and synthetic cannabinoids. In this review, the main …
[HTML][HTML] Development and characterization of nanostructured lipid carriers for cannabidiol delivery
R Vardanega, FL Lüdtke, L Loureiro, RFS Gonçalves… - Food Chemistry, 2024 - Elsevier
This study evaluated the physicochemical characteristics of nanostructured lipid carriers
(NLCs) as a potential vehicle for cannabidiol (CBD), a lipophilic molecule with great …
(NLCs) as a potential vehicle for cannabidiol (CBD), a lipophilic molecule with great …
[HTML][HTML] Strategies to improve cannabidiol bioavailability and drug delivery
SE O'Sullivan, SS Jensen, AR Kolli, GN Nikolajsen… - Pharmaceuticals, 2024 - mdpi.com
The poor physicochemical properties of cannabidiol (CBD) hamper its clinical development.
The aim of this review was to examine the literature to identify novel oral products and …
The aim of this review was to examine the literature to identify novel oral products and …
Solubility-enabling formulations for oral delivery of lipophilic drugs: considering the solubility-permeability interplay for accelerated formulation development
N Fine-Shamir, A Dahan - Expert Opinion on Drug Delivery, 2024 - Taylor & Francis
Introduction Tackling low water solubility of drug candidates is a major challenge in today's
pharmaceutics/biopharmaceutics, especially by means of modern solubility-enabling …
pharmaceutics/biopharmaceutics, especially by means of modern solubility-enabling …
[HTML][HTML] Amphiphilic block copolymers bearing fatty acid derivatives as vehicles for THC in the development of analgesic oral formulations
JD Porras, Y Román, J Palacio… - Reactive and Functional …, 2024 - Elsevier
Cannabis-based therapeutics have gained increasing attention for their potential health
benefits; however, the efficient administration of hydrophobic constituents such as Δ9 …
benefits; however, the efficient administration of hydrophobic constituents such as Δ9 …