The chemistry of 1, 3, 4-thiadiazole is one of the most interesting scaffolds for synthesizing
new drug molecules due to their numerous pharmacological activities. Several modifications …

This review meticulously examines the synthesis techniques for 1, 3, 4-thiadiazole
derivatives, focusing on cyclization, condensation reactions and functional group …

In this work, the synthesis, characterization, and biological activities of a new series of 1, 3, 4‐
thiadiazole derivatives were investigated. The structures of final compounds were identified …

Succinate dehydrogenase (SDH), a pivotal enzyme linking the respiratory electron transport
chain and tricarboxylic acid (TCA) cycle, has been identified as an ideal target for …

A new quinoline alkaloid, 5‐hydroxy‐6‐methoxy‐N‐methyl‐2‐phenylquinoline‐4‐one (1),
and seventeen known quinoline alkaloids (2–18) were isolated from the roots of Orixa …

In order to discover novel compounds with excellent agricultural activities, novel flavonol
derivatives containing 1, 3, 4-thiadiazole were synthesized and evaluated for their antifungal …

In this study, 24 novel ferulic acid derivatives containing 1, 3, 4-oxadiazole thioether and
trifluoromethyl pyrimidine were designed and synthesized. Bioactivity assay showed that …

To explore more efficient and less toxic antibacterial and antifungal pesticides, we utilized 2,
6-difluorobenzamide as a starting material and ultimately synthesized 23 novel benzoylurea …

Derivatives of 1, 3, 4-thiadiazole are of great interest for scientific and practical human
activities as biologically active substances, dyes, components for creating semiconductors …