Transforming growth factor-β (TGF-β) signaling has a paradoxical role in cancer
progression, and it acts as a tumor suppressor in the early stages but a tumor promoter in …

The serine/threonine phosphatase PP2A regulates a vast portion of the phosphoproteome
including pathways involved in apoptosis, proliferation and DNA damage response and …

This study aimed to determine the association between non‐high‐fat diet‐induced obesity‐
(non‐DIO‐) associated gut microbiome dysbiosis with gut abnormalities like cellular turnover …

Deltamethrin (DLM) is widely used in agriculture and the prevention of human insect-borne
diseases. However, the molecular mechanism of DLM induced liver injury remains unclear …

Role of gut microbiome in obesity and type 2 diabetes (T2D) became apparent from several
independent studies indicating that gut microbiome modulators like prebiotics may improve …

Peripheral regulatory T (pTreg) cells are a key T cell lineage for mucosal immune tolerance
and anti-inflammatory responses, and interleukin-2 receptor (IL-2R) signaling is critical for …

Aging-related abnormalities in gut microbiota are associated with cognitive decline,
depression, and anxiety, but underlying mechanisms remain unstudied. Here, our study …

FoxO transcription factors serve as the central regulator of cellular homeostasis and are
tumor suppressors in human cancers. Recent studies have revealed that, besides their …

TGFβ is involved in various biological processes, including development, differentiation,
growth regulation, and epithelial–mesenchymal transition (EMT). In TGFβ/Smad signaling …

FOXO proteins are a sub-group of a superfamily of forkhead box (FOX)-containing
transcription factors (TFs). FOXOs play an important role in regulating a plethora of …