[HTML][HTML] Immunity to RSV in early-life

L Lambert, AM Sagfors, PJM Openshaw… - Frontiers in …, 2014 - frontiersin.org
Respiratory Syncytial Virus (RSV) is the commonest cause of severe respiratory infection in
infants, leading to over 3 million hospitalizations and around 66,000 deaths worldwide each …

Neonatal and early life vaccinology

CA Siegrist - Vaccine, 2001 - Elsevier
Preclinical and human vaccine studies indicate that, although neonatal immunisation does
not generally lead to rapid and strong antibody responses, it may result in an efficient …

Addressing parents' concerns: do multiple vaccines overwhelm or weaken the infant's immune system?

PA Offit, J Quarles, MA Gerber, CJ Hackett… - …, 2002 - publications.aap.org
Recent surveys found that an increasing number of parents are concerned that infants
receive too many vaccines. Implicit in this concern is that the infant's immune system is …

Mechanisms by which maternal antibodies influence infant vaccine responses: review of hypotheses and definition of main determinants

CA Siegrist - Vaccine, 2003 - Elsevier
Several mechanisms have been suggested as mediating the inhibitory influence of maternal
antibodies (MatAb) on infant responses. This inhibition is B cell determinant-specific …

[HTML][HTML] Structure-guided design of an anti-dengue antibody directed to a non-immunodominant epitope

LN Robinson, K Tharakaraman, KJ Rowley, VV Costa… - Cell, 2015 - cell.com
Dengue is the most common vector-borne viral disease, causing nearly 400 million
infections yearly. Currently there are no approved therapies. Antibody epitopes that elicit …

[HTML][HTML] Maternal antibodies inhibit neonatal and infant responses to vaccination by shaping the early-life B cell repertoire within germinal centers

M Vono, CS Eberhardt, F Auderset, B Mastelic-Gavillet… - Cell reports, 2019 - cell.com
Maternal antibodies (MatAbs) protect offspring from infections but limit their responses to
vaccination. The mechanisms of this inhibition are still debated. Using murine early-life …

[HTML][HTML] Strategies for design and application of enteric viral vaccines

KS Chattha, JA Roth, LJ Saif - Annu. Rev. Anim. Biosci., 2015 - annualreviews.org
Enteric viral infections in domestic animals cause significant economic losses. The recent
emergence of virulent enteric coronaviruses [porcine epidemic diarrhea virus (PEDV)] in …

Passive transmission and persistence of naturally acquired or vaccine-induced maternal antibodies against measles in newborns

E Leuridan, P Van Damme - Vaccine, 2007 - Elsevier
This paper reviews literature on passively transferred maternal antibodies against measles
in infants. The amount and decay of these antibodies can be a result of changing patterns in …

Equine influenza virus infections: an update

C Van Maanen, A Cullinane - Veterinary Quarterly, 2002 - Taylor & Francis
Equine influenza is one of the most economically important contagious respiratory diseases
of horses. In this paper the current state of knowledge of equine influenza virus and the most …

Vaccination in the neonatal period and early infancy

CA Siegrist - International reviews of immunology, 2000 - Taylor & Francis
Immune maturation is responsible for a progressive increase in antibody responses that can
be elicited during the first year of life, such that neonatal immunization may currently not be …