Background There is growing evidence supporting the efficacy of shorter courses of
antibiotic therapy for common infections. However, the risks of prolonged antibiotic duration …

Complicated community-acquired pneumonia in a previously well child is a severe illness
characterised by combinations of local complications (eg, parapneumonic effusion …

Objectives To develop evidence-based recommendations for clinicians caring for children
(including infants, school-aged children, and adolescents) with septic shock and other …

The European Society for Paediatric Infectious Diseases (ESPID) Bone and Joint Infection
Guidelines (ESPID Guidelines) are intended for use by health providers who take care of …

Abstract Background Non-typhoidal Salmonella (NTS) are a frequent cause of invasive
infections in sub-Saharan Africa. They are frequently multidrug resistant (co-resistant to …

There is a clear need for simple resources to improve the quality of antibiotic prescribing
globally. The AWaRe book was designed as a tool to make the antibiotics section of the …

The kidneys and the urinary tract are a common source of infection in children of all ages,
especially infants and young children. The main risk factors for sequelae after urinary tract …

Antibiotics are recognized widely for their benefits when used appropriately. However, they
are often used inappropriately despite the importance of responsible use within good clinical …

Background In children, necrotizing pneumonia (NP) is an uncommon, severe complication
of pneumonia. It is characterized by destruction of the underlying lung parenchyma resulting …

UK good practice recommendations for outpatient parenteral antimicrobial therapy (OPAT)
were published in 2012 and 2015 for adult and paediatric patients, respectively. Here we …