Targeting and engineering long non-coding RNAs for cancer therapy

M Coan, S Haefliger, S Ounzain, R Johnson - Nature Reviews Genetics, 2024 - nature.com
RNA therapeutics (RNATx) aim to treat diseases, including cancer, by targeting or
employing RNA molecules for therapeutic purposes. Amongst the most promising targets …

[HTML][HTML] Long non-coding RNAs and their “discrete” contribution to IBD and Johne's disease—What stands out in the current picture? A comprehensive review

KA Triantaphyllopoulos - International Journal of Molecular Sciences, 2023 - mdpi.com
Non-coding RNAs (ncRNA) have paved the way to new perspectives on the regulation of
gene expression, not only in biology and medicine, but also in associated fields and …

[PDF][PDF] Innovative therapeutic strategies to overcome radioresistance in breast cancer

CR Arnold, J Mangesius, I Portnaia… - Frontiers in …, 2024 - frontiersin.org
Enhanced understanding of the molecular basis of radioresistance paves the way for novel
therapeutic interventions, potentially translatable into clinical applications. This section …

Nanotherapeutic approaches for delivery of long non-coding RNAs: an updated review with emphasis on cancer

F Davodabadi, S Mirinejad, S Malik, A Dhasmana… - Nanoscale, 2024 - pubs.rsc.org
The long noncoding RNAs (lncRNAs) comprise a wide range of RNA species whose length
exceeds 200 nucleotides, which regulate the expression of genes and cellular functions in a …

Tumor-derived lncRNAs; Behind-the-scenes mediators that modulate the immune system and play a role in cancer pathogenesis

SIS Al-Hawary, RO Saleh, SG Taher, SM Ahmed… - … -Research and Practice, 2024 - Elsevier
Having been involved in complex cellular regulatory networks and cell-to-cell
communications, non-coding RNAs (lncRNAs) have become functional carriers that transmit …