Short-chain fatty acids (SCFAs) play a key role in health and disease, as they regulate gut
homeostasis and their deficiency is involved in the pathogenesis of several disorders …

Our ancestral diet consisted of much more nondigestible fiber than that of many societies
today. Thus, from an evolutionary perspective the human genome and its physiological and …

The gut microbiome is an important determinant in various diseases. Here we perform a
cross-sectional study of Japanese adults and identify the Blautia genus, especially B …

Diet and dietary components have profound effects on the composition of the gut microbiota
and are among the most important contributors to the alteration in bacterial flora. This review …

Peroxisome proliferator-activated receptor-α (PPARα), PPARδ and PPARγ are transcription
factors that regulate gene expression following ligand activation. PPARα increases cellular …

Dietary fibre has long been established as a nutritionally important, health-promoting food
ingredient. Modern dietary practices have seen a significant reduction in fibre consumption …

The human gut microbiota has received considerable interest in the recent years and our
knowledge of the inhabitant species and their potential applications is increased particularly …

Metabolic disorders represent a growing worldwide health challenge due to their
dramatically increasing prevalence. The gut microbiota is a crucial actor that can interact …

Short-chain fatty acids (SCFAs), particularly acetate, propionate and butyrate, are mainly
produced by anaerobic fermentation of gut microbes. SCFAs play an important role in …

The gastrointestinal tract plays a role in the development and treatment of metabolic
diseases. During a meal, the gut provides crucial information to the brain regarding …