Fibromyalgia is a syndrome characterized by chronic and widespread musculoskeletal pain,
often accompanied by other symptoms, such as fatigue, intestinal disorders and alterations …

The prefrontal cortex (PFC) is not only important in executive functions, but also pain
processing. The latter is dependent on its connections to other areas of the cerebral …

Pain can be both a cause and a consequence of sleep deficiency. This bidirectional
relationship between sleep and pain has important implications for clinical management of …

Endometriosis is a chronic, inflammatory disease affecting more than 170 million women
worldwide and up to 10% of women of reproductive age. As a consequence of inflammatory …

In 2006, the OPPERA project (Orofacial Pain: Prospective Evaluation and Risk Assessment)
set out to identify risk factors for development of painful temporomandibular disorder (TMD) …

Several randomized controlled trials have implemented cognitive behavioral therapy for
insomnia (CBT-I) for patients with comorbid insomnia and chronic pain. This systematic …

Chronic pain is a common public health problem that has a detrimental impact on patient
health, quality of life (QoL), and function, and poses a substantial socioeconomic burden …

The role of peripheral physiology in the experience of emotion has been debated since the
19th century following the seminal proposal by William James that somatic responses to …

The psychosocial and functional consequences of chronic pain disorders have been well
documented as having significant effects on the experience of pain, presentation to health …

Objectives Chronic pain, with or without an identified diagnosis or cause, is widespread and
commonly associated with sleep disturbances. However, research has often used poor …