Delivery strategies for sustained drug release in the lungs
C Loira-Pastoriza, J Todoroff, R Vanbever - Advanced drug delivery reviews, 2014 - Elsevier
Drug delivery to the lungs by inhalation offers a targeted drug therapy for respiratory
diseases. However, the therapeutic efficacy of inhaled drugs is limited by their rapid …
diseases. However, the therapeutic efficacy of inhaled drugs is limited by their rapid …
Lipid based nanocarriers: a translational perspective
Over the recent couple of decades, pharmaceutical field has embarked most phenomenal
noteworthy achievements in the field of medications as well as drug delivery. The rise of …
noteworthy achievements in the field of medications as well as drug delivery. The rise of …
Increasing complexity and interactions of oxidative stress in chronic respiratory diseases: an emerging need for novel drug delivery systems
Oxidative stress is intensely involved in enhancing the severity of various chronic respiratory
diseases (CRDs) including asthma, chronic obstructive pulmonary disease (COPD) …
diseases (CRDs) including asthma, chronic obstructive pulmonary disease (COPD) …
[HTML][HTML] Micro and nano-carriers-based pulmonary drug delivery system: Their current updates, challenges, and limitations–A review
M Kumar, AR Hilles, SHA Almurisi, A Bhatia… - JCIS Open, 2023 - Elsevier
The lung is an attractive target for drug delivery because of the ease of non-invasive
administration via inhalation, bypassing metabolism in the liver, direct delivery to the …
administration via inhalation, bypassing metabolism in the liver, direct delivery to the …
Enhancing the therapeutic use of biofilm-dispersing enzymes with smart drug delivery systems
Biofilm-dispersing enzymes degrade the extracellular polymeric matrix surrounding bacterial
biofilms, disperse the microbial community and increase their susceptibility to antibiotics and …
biofilms, disperse the microbial community and increase their susceptibility to antibiotics and …
Biodegradable polymeric nanocarriers for pulmonary drug delivery
E Rytting, J Nguyen, X Wang… - Expert opinion on drug …, 2008 - Taylor & Francis
Background: Pulmonary drug delivery is attractive for both local and systemic drug delivery
as a non-invasive route that provides a large surface area, thin epithelial barrier, high blood …
as a non-invasive route that provides a large surface area, thin epithelial barrier, high blood …
Scope and relevance of a pulmonary biopharmaceutical classification system AAPS/FDA/USP Workshop March 16-17th, 2015 in Baltimore, MD
JE Hastedt, P Bäckman, AR Clark, W Doub, A Hickey… - 2016 - Springer
Abstract The Biopharmaceutics Classification System (BCS), developed in the 1990s for oral
immediate release drugs, is utilized by R&D scientists and regulators to streamline product …
immediate release drugs, is utilized by R&D scientists and regulators to streamline product …
Paclitaxel loaded PEG5000–DSPE micelles as pulmonary delivery platform: formulation characterization, tissue distribution, plasma pharmacokinetics, and …
KK Gill, S Nazzal, A Kaddoumi - European Journal of Pharmaceutics and …, 2011 - Elsevier
The objective of the present study was to evaluate the potential of paclitaxel loaded micelles
fabricated from PEG5000–DSPE as a sustained release system following pulmonary …
fabricated from PEG5000–DSPE as a sustained release system following pulmonary …
Smart lipid nanoparticles containing levofloxacin and DNase for lung delivery. Design and characterization
Levofloxacin (LV) is a hydrophilic broad-spectrum antibiotic commonly used in pulmonary
treatment against recurrent infections of Pseudomonas aeruginosa, and particularly in cystic …
treatment against recurrent infections of Pseudomonas aeruginosa, and particularly in cystic …
Solid lipid microparticles as an approach to drug delivery
Introduction: Solid lipid particles were introduced in the early 1990s as an alternative drug
carrier system to emulsions, liposomes and polymeric microparticles. Although lipid …
carrier system to emulsions, liposomes and polymeric microparticles. Although lipid …