Vascular endothelial cells and innate immunity
In addition to the roles of endothelial cells (ECs) in physiological processes, ECs actively
participate in both innate and adaptive immune responses. We previously reported that, in …
participate in both innate and adaptive immune responses. We previously reported that, in …
[HTML][HTML] An evolving new paradigm: endothelial cells–conditional innate immune cells
Endothelial cells (ECs) are a heterogeneous population that fulfills many physiological
processes. ECs also actively participate in both innate and adaptive immune responses …
processes. ECs also actively participate in both innate and adaptive immune responses …
Angiotensin II AT1 receptor blockers as treatments for inflammatory brain disorders
JM Saavedra - Clinical science, 2012 - portlandpress.com
The effects of brain AngII (angiotensin II) depend on AT1 receptor (AngII type 1 receptor)
stimulation and include regulation of cerebrovascular flow, autonomic and hormonal …
stimulation and include regulation of cerebrovascular flow, autonomic and hormonal …
The vascular endothelium: A regulator of arterial tone and interface for the immune system
R Khaddaj Mallat, C Mathew John… - Critical reviews in …, 2017 - Taylor & Francis
As the primary interface between the blood and various tissues of the body, the vascular
endothelium exhibits a diverse range of roles and activities, all of which contribute to the …
endothelium exhibits a diverse range of roles and activities, all of which contribute to the …
PCSK9 siRNA inhibits HUVEC apoptosis induced by ox-LDL via Bcl/Bax–caspase9–caspase3 pathway
CY Wu, ZH Tang, L Jiang, XF Li, ZS Jiang… - Molecular and cellular …, 2012 - Springer
This paper investigated the effects of ox-LDL on PCSK9, and the molecular mechanisms of
PCSK9 siRNA-inhibited apoptosis induced by ox-LDL in human umbilical vein endothelial …
PCSK9 siRNA-inhibited apoptosis induced by ox-LDL in human umbilical vein endothelial …
[HTML][HTML] Role of vascular smooth muscle cell in the inflammation of atherosclerosis
S Lim, S Park - BMB reports, 2014 - ncbi.nlm.nih.gov
Atherosclerosis is a pathologic process occurring within the artery, in which many cell types,
including T cell, macrophages, endothelial cells, and smooth muscle cells, interact, and …
including T cell, macrophages, endothelial cells, and smooth muscle cells, interact, and …
Anthocyanins and their physiologically relevant metabolites alter the expression of IL‐6 and VCAM‐1 in CD40L and oxidized LDL challenged vascular endothelial …
HP Amin, C Czank, S Raheem, Q Zhang… - Molecular nutrition & …, 2015 - Wiley Online Library
Scope In vitro and in vivo studies suggest that dietary anthocyanins modulate cardiovascular
disease risk; however, given anthocyanins extensive metabolism, it is likely that their …
disease risk; however, given anthocyanins extensive metabolism, it is likely that their …
Acute atrial tachyarrhythmia induces angiotensin II type 1 receptor-mediated oxidative stress and microvascular flow abnormalities in the ventricles
A Goette, A Bukowska, D Dobrev… - European heart …, 2009 - academic.oup.com
Aims Patients with paroxysmal atrial fibrillation (AF) often present with typical angina
pectoris and mildly elevated levels of cardiac troponin (non ST-segment elevation …
pectoris and mildly elevated levels of cardiac troponin (non ST-segment elevation …
Activation of TRPV1 reduces vascular lipid accumulation and attenuates atherosclerosis
L Ma, J Zhong, Z Zhao, Z Luo, S Ma, J Sun… - Cardiovascular …, 2011 - academic.oup.com
Aims Activation of transient receptor potential vanilloid type-1 (TRPV1) channels may affect
lipid storage and the cellular inflammatory response. Now, we tested the hypothesis that …
lipid storage and the cellular inflammatory response. Now, we tested the hypothesis that …
Dual signaling evoked by oxidized LDLs in vascular cells
A Nègre-Salvayre, N Augé, C Camaré… - Free Radical Biology …, 2017 - Elsevier
The oxidative theory of atherosclerosis relies on the modification of low density lipoproteins
(LDLs) in the vascular wall by reactive oxygen species. Modified LDLs, such as oxidized …
(LDLs) in the vascular wall by reactive oxygen species. Modified LDLs, such as oxidized …