A combination of approaches has begun to elucidate the mechanisms of gastrointestinal
development. This review describes progress over the last 20 years in understanding …

Chylomicrons are lipoproteins synthesized exclusively by the intestine to transport dietary fat
and fat-soluble vitamins. Synthesis of apoB48, a translational product of the apob gene, is …

Germ line transformation of white− Drosophila embryos with P-element vectors containing
white expression cassettes results in flies with different eye color phenotypes due to position …

We have previously reported a positive correlation between the expression of BHMT
(betaine–homocysteine S-methyltransferase) and ApoB (apolipoprotein B) in rat hepatoma …

Over the past five years, several laboratories have used a variety of transgenic and gene-
targeted mice to study apoB. These studies have helped in 1) generating new mouse …

We reported previously that∼ 80-kilobase pair (kb) P1 bacteriophage clones spanning
either the human or mouse apoB gene (clones p158 and p649, respectively) confer apoB …

Transcription factors are important in regulating gene expression, and their analysis is of
paramount interest to molecular biologists studying this area. This book looks at the basic …

Plasma lipoproteins (LPs) are soluble aggregates of lipids and proteins that deliver
hydrophobic, water-insoluble lipids (triacylglycerols (TGs) and cholesteryl esters (CEs)) from …

Cholesterol 7α-hydroxylase is the rate-limiting enzyme in the degradation of cholesterol to
bile salts and plays a central role in regulating cholesterol homeostasis. The mechanisms …

Prior studies have established that the expression of the human apolipoprotein B (apoB)
gene in the intestine is dependent on DNA sequences located a great distance from the …