Preclinical formulations for discovery and toxicology: physicochemical challenges

S Neervannan - Expert opinion on drug metabolism & toxicology, 2006 - Taylor & Francis
Formulations play a key role in assessing the biological properties of a molecule during drug
discovery. Maximising exposure is the primary objective in early animal experimentation, so …

The development of a pharmaceutical oral solid dosage forms

R Shaikh, DP O'Brien, DM Croker… - Computer Aided Chemical …, 2018 - Elsevier
Among the various drug delivery routes, the oral route has long been the most popular and
convenient route. In this chapter, we focus on the development of oral solid dosage forms …

Polymeric ocular nanosuspension for controlled release of acyclovir: in vitro release and ocular distribution

P Dandagi, S Kerur, V Mastiholimath… - Iranian Journal of …, 2009 - brieflands.com
: The aim of this study is to formulate a novel ophthalmic nanosuspension (ONS), an
alternative carrier system to traditional colloidal carriers for controlled release (CR) of …

[PDF][PDF] Effect of packaging on stability of drugs and drug products

EO Akala - Pharmaceutical manufacturing handbook: regulations …, 2008 - academia.edu
Effect of packaging on stability of drugs and drug products Page 657 641 7.3 EFFECT OF
PACKAGING ON STABILITY OF DRUGS AND DRUG PRODUCTS Emmanuel O. Akala School …

Preformulation aspects of insoluble compounds

WQT Tong, H Wen - Water-insoluble drug formulation, 2018 - taylorfrancis.com
This chapter discusses the theoretical and practical considerations for the preformulation of
insoluble compounds and reviews the experimental methods that are applicable to the …

[DOC][DOC] Peningkatan Kelarutan Kuersetin Melalui Pembentukan Kompeks Inklusi Dengan?-Siklodekstrin

S Syofyan, L Henny, B Amri - Jurnal sains dan teknologi …, 2008 - repository.unand.ac.id
Quercetin, a chemical cousin of the glycoside rutin from Manihot esculenta Crantz, is
appears to have many biologically active. Preformulation studies are usually associated for …

Effect of hydrophilic polymer and binder on drug release of metformin HCl sustained release tablet

SB Kakad, PR Rachh - International Journal Of Health Sciences, 2022 - neliti.com
To develop an oral sustained release Metformin HCl tablet by wet granulation technique,
using different grades of hydroxyl propyl methylcellulose (HPMC) in different concentration …

Development and evaluation of theophylline microballoons drug delivery system

RD Yachawad - 2012 - search.proquest.com
The objective of this research work was to develop and evaluate the theophylline
microballoons drug delivery system by using ionotropic gelation method. The floating …

[PDF][PDF] Role of preformulation in development of solid dosage forms

OP Perumal, SK Podaralla - … Manufacturing Handbook: Production …, 2008 - academia.edu
6.2. 2 Physical/Bulk Characteristics 6.2. 2.1 Crystallinity and Polymorphism 6.2. 2.2
Hydrates/Solvates 6.2. 2.3 Amorphates 6.2. 2.4 Hygroscopicity 6.2. 2.5 Particle …

[PDF][PDF] Design, development and evaluation of press coated tablets of an eprosartan mesylate

S Rewar, BK Bansal, CJ Singh… - … of Pharmaceutical and …, 2014 - researchgate.net
The chronopharmacotherapy drug delivery system is widely used for treatment of diseases
occurs due to circadian changes in the body the body. This system is aims to release drugs …