[HTML][HTML] Chemical neuroanatomical and psychopharmacological evidence that κ receptor-mediated endogenous opioid peptide neurotransmission in the dorsal and …

JA da Silva, RL de Freitas, GCD Eichenberger… - European journal of …, 2013 - Elsevier
The chemical neuroanatomy and the effects of central administration of opioid antagonists
on the innate fear-induced responses elicited by electrical (at escape behaviour threshold) …

The long-term effects of Δ9-tetrahydrocannabinol on microtubule dynamicity in rats

D Gholami, AR Noori, M Mohammadkhani… - Archives of Biochemistry …, 2020 - Elsevier
Studies reported that Δ 9-tetrahydrocannabinol (Δ 9-THC) is an essential drug as an anti-
cancer, neuroprotective, anti-inflammatory, and immune-modulatory agent. However, the …

Blockade of synaptic activity in the neostriatum and activation of striatal efferent pathways produce opposite effects on panic attack-like defensive behaviours evoked …

JA da Silva, RC Almada, RM de Figueiredo… - Physiology & …, 2018 - Elsevier
The dorsal periaqueductal grey matter (dPAG) and the deep layers of the superior colliculus
(dlSC) have been implicated in the organisation of innate fear-related defensive behaviours …

Cannabidiol in the dorsal hippocampus attenuates emotional and cognitive impairments related to neuropathic pain: Role of prelimbic neocortex-hippocampal …

AC Medeiros, P Medeiros, GR Pigatto, S Maione… - Progress in Neuro …, 2024 - Elsevier
Background and purpose Chronic neuropathic pain (NP) is commonly associated with
cognitive and emotional impairments. Cannabidiol (CBD) presents a broad spectrum of …

The alpha-and beta-noradrenergic receptors blockade in the dorsal raphe nucleus impairs the panic-like response elaborated by medial hypothalamus neurons

A Uribe-Marino, MA Castiblanco-Urbina… - Brain Research, 2019 - Elsevier
Dorsal raphe nucleus (DRN) neurons are reciprocally connected to the locus coeruleus (LC)
and send neural pathways to the medial hypothalamus (MH). The aim of this work was to …

The blockade of µ1-and κ-opioid receptors in the inferior colliculus decreases the expression of panic attack-like behaviours induced by chemical stimulation of the …

F Calvo, RC Almada, JA da Silva, P Medeiros… - …, 2019 - karger.com
Background: Gamma-aminobutyric acid (GABA) ergic and opioid systems play a crucial role
in the neural modulation of innate fear organised by the inferior colliculus (IC). In addition …

Análise das evidências científicas do uso do canabidiol em doenças psiquiátricas e neurológicas

R Costa - 2017 - repositorio.ufsc.br
INTRODUÇÃO: O uso de Cannabis sativa é relatado nas sociedades egípcia, chinesa,
assíria e hindu há cerca de 10 mil anos. Originária da Ásia Central, essa planta se espalhou …

The blockade of μ‑opioid receptors in the lateral hypothalamus enhances panic attack‑like behaviour and diminishes defensive antinociception

B Fernandes, D Avila, V Santana, T Maffei… - Acta Neurobiologiae …, 2022 - ane.pl
The lateral hypothalamus (LH) sends neural pathways to structures involved on predator‑
related defensive behaviours, escape and antinociception. The aim of this study was to …

Endocannabinoid neuromodulation in the neostriatum decreases the GABAergic striato-nigral disinhibitory function and increases the nigro-collicular inhibitory …

JA da Silva, RC Almada, YB de Paiva… - Journal of Neural …, 2020 - Springer
We previously reported the involvement of neostriato-nigral projections in the organisation of
innate fear and panic attack-like responses organised by dorsal midbrain neurons, such as …

Cannabinoids help to unravel etiological aspects in common and bring hope for the treatment of autism and epilepsy

R Malcher-Lopes - Revista da Biologia, 2014 - revistas.usp.br
Since 1843 the anticonvulsant properties of Cannabis are known by the Western science. In
1980, clinical trials have shown that cannabidiol has antiepileptic activity in refractory …