Scars caused by skin injuries after burns, wounds, abrasions and operations have serious
physical and psychological effects on patients. In recent years, the research of scar free …

Delayed wound healing is one of the most global public health threats affecting nearly 100
million people each year, particularly the chronic wounds. Many confounding factors such as …

Background Angiogenesis and tissue repair in chronic non-healing diabetic wounds remain
critical clinical problems. Engineered MSC-derived exosomes have significant potential for …

Senescent cells persist and continuously secrete proinflammatory and tissue-remodeling
molecules that poison surrounding cells, leading to various age-related diseases, including …

Autophagy is an evolutionarily conserved process that plays a role in regulating
homeostasis under physiological conditions. However, dysregulation of autophagy is …

Impaired wound healing is one of the severe complications of diabetes. Macrophages have
been shown to play a vital role in wound healing. In different wound environments …

Autophagy is an explicit cellular process to deliver dissimilar cytoplasmic misfolded proteins,
lipids and damaged organelles to the lysosomes for degradation and elimination. The …

As a highly regulated and dynamically balanced intracellular degradation mechanism,
macroautophagy/autophagy plays an essential housekeeping role in different successive …

Background Amphibian-derived peptides exhibit considerable potential in the discovery and
development of new therapeutic interventions for clinically challenging chronic skin wounds …

Background Bacterial invasion, protracted inflammation, and angiogenesis inhibition are
hallmarks of chronic diabetic wounds, bringing about patient morbidity and rising healthcare …