[HTML][HTML] Inflammation and gastric cancer

A Jaroenlapnopparat, K Bhatia, S Coban - Diseases, 2022 - mdpi.com
Gastric cancer remains a major killer globally, although its incidence has declined over the
past century. It is the fifth most common cancer and the third most common reason for cancer …

[HTML][HTML] A sweet warning: mucin-type O-glycans in cancer

Y Zhang, L Sun, C Lei, W Li, J Han, J Zhang, Y Zhang - Cells, 2022 - mdpi.com
Glycosylation is a common post-translational modification process of proteins. Mucin-type O-
glycosylation is an O-glycosylation that starts from protein serine/threonine residues …

[HTML][HTML] Establishment of a novel lysosomal signature for the diagnosis of gastric cancer with in-vitro and in-situ validation

Q Wang, Y Liu, Z Li, Y Tang, W Long, H Xin… - Frontiers in …, 2023 - frontiersin.org
Background Gastric cancer (GC) represents a malignancy with a multi-factorial combination
of genetic, environmental, and microbial factors. Targeting lysosomes presents significant …

[HTML][HTML] MUC1 expressions and its prognostic values in US gastric cancer patients

YI Kim, RL Pecha, T Keihanian, M Mercado… - Cancers, 2023 - mdpi.com
Simple Summary Although the alteration of mucin (MUC) expression was associated with
gastric cancer (GC) prognosis, its prognostic values remain to be elucidated in US GC …

[HTML][HTML] GATA4 forms a positive feedback loop with CDX2 to transactivate MUC2 in bile acids-induced gastric intestinal metaplasia

X Yang, T Ye, L Rong, H Peng, J Tong, X Xiao… - Gut and …, 2024 - ncbi.nlm.nih.gov
Methods The expression of GATA4 in bile acid-induced cell models and human specimens
was examined. The transcriptional regulation of GATA4 was investigated by chromatin …

A unified DNA‐and RNA‐based NGS strategy for the analysis of multiple types of variants at the dual nucleic acid level in solid tumors

H Chen, B Wang, Y Zhang, Y Shu… - Journal of Clinical …, 2023 - Wiley Online Library
Background Targeted next‐generation sequencing (NGS) is a powerful and suitable
approach to comprehensively identify multiple types of variants in tumors. RNA‐based NGS …

[HTML][HTML] Differential cytokine expression in gastric tissues highlights helicobacter pylori's role in gastritis

XT Yang, PQ Niu, XF Li, MM Sun, W Wei, YQ Chen… - Scientific Reports, 2024 - nature.com
Abstract Helicobacter pylori (H. pylori), known for causing gastric inflammation, gastritis and
gastric cancer, prompted our study to investigate the differential expression of cytokines in …

Comparative study on genomic and epigenomic profiles of retinoblastoma or tuberous sclerosis complex via nanopore sequencing and a joint screening framework

J Wang, C Zhang, L Zhang, H Yao, X Liu, Y Shi… - Cancer Gene …, 2024 - nature.com
Recurrence and extraocular metastasis in advanced intraocular retinoblastoma (RB) are still
major obstacles for successful treatment of Chinese children. Tuberous sclerosis complex …

Quantitative Analysis on Molecular Characteristics Evolution of Gastric Cancer Progression and Prognosis

Y Hu, X Lv, W Wei, X Li, K Zhang, L Zhu… - Advanced …, 2023 - Wiley Online Library
The dynamic changes of key biological characteristics from gastric low‐grade intraepithelial
neoplasia (LGIN) to high‐grade intraepithelial neoplasia (HGIN) to early gastric cancer …

Dynamic variations of the gastric microbiota: Key therapeutic points in the reversal of Correa's cascade

J Xi, Y Li, H Zhang, Z Bai - International Journal of Cancer, 2023 - Wiley Online Library
Correa's cascade is a dynamic process in the development of intestinal‐type gastric cancer
(GC), and its pathological features, gastric microbiota and interactions between …