Highlights (AQPs) are transmembrane proteins responsible for fast water movement across
cell membranes, including those of astrocytes. The expression and subcellular localization …

The glymphatic system, a fluid-clearance pathway involved in brain waste clearance, is
known to be impaired in neurological disorders, including Alzheimer's disease (AD). For this …

Background Maintaining the structural and functional integrity of the blood–brain barrier
(BBB) is vital for neuronal equilibrium and optimal brain function. Disruptions to BBB …

The cells of the choroid plexus (CP) epithelium are specialized ependymal cells (ECs) but
have distinct properties. The CP cells and ECs form single‐cell sheets contiguous to each …

Aquaporins (AQPs; AQP0–AQP12) are water channels expressed in many and diverse cell
types, participating in various functions of cells, tissues, and systems, including the central …

Aquaporins (AQPs), particularly AQP4, play a crucial role in regulating fluid dynamics in the
brain, impacting the development and resolution of edema following traumatic brain injury …

AQP4 is expressed in the endfeet membranes of subpial and perivascular astrocytes and in
the ependymal cells that line the ventricular system. The sporadic appearance of obstructive …

Background Although many pathological mechanisms and etiological hypotheses of acute
unilateral vestibulopathy (AUVP) have been reported, but the actual etiology remains to be …

Ischemic stroke is a leading cause of adult disability and death worldwide. The primary
treatment for cerebral ischemia patients is to restore blood supply to the ischemic region as …

Water is an abundant and important component of the human brain, the homeostasis of
which is rigorously controlled. Aquaporins (AQPs) play a key role in mediating most water …