[HTML][HTML] Prenatal effects of nicotine on obesity risks: a narrative review

O White, N Roeder, K Blum, RD Eiden… - International journal of …, 2022 - mdpi.com
Nicotine usage by mothers throughout pregnancy has been observed to relate to numerous
deleterious effects in children, especially relating to obesity. Children who have prenatally …

[HTML][HTML] Precision behavioral management (PBM) and cognitive control as a potential therapeutic and prophylactic modality for reward deficiency syndrome (RDS): is …

MA Madigan, A Gupta, A Bowirrat, D Baron… - International Journal of …, 2022 - mdpi.com
This brief commentary aims to provide an overview of the available and relatively new
precision management of reward deficiencies manifested as substance and behavioral …

[HTML][HTML] The first exploratory personalized medicine approach to improve bariatric surgery outcomes utilizing psychosocial and genetic risk assessments: encouraging …

PK Thanos, C Hanna, A Mihalkovic… - Journal of Personalized …, 2023 - mdpi.com
It is predicted that by 2030, globally, an estimated 2.16 billion adults will be overweight, and
1.12 billion will be obese. This study examined genetic data regarding Reward Deficiency …

[HTML][HTML] Proposing a “brain health checkup (BHC)” as a global potential “standard of care” to overcome reward dysregulation in primary care medicine: Coupling …

ER Braverman, CA Dennen, MS Gold… - International Journal of …, 2022 - mdpi.com
In 2021, over 100,000 people died prematurely from opioid overdoses. Neuropsychiatric
and cognitive impairments are underreported comorbidities of reward dysregulation due to …

[HTML][HTML] Should reward deficiency syndrome (RDS) be considered an umbrella disorder for mental illness and associated genetic and epigenetic induced …

K Blum, CA Dennen, I Elman, A Bowirrat… - Journal of Personalized …, 2022 - mdpi.com
Reward Deficiency Syndrome (RDS) is defined as a breakdown of reward
neurotransmission that results in a wide range of addictive, compulsive, and impulsive …

[HTML][HTML] Genetic addiction risk and psychological profiling analyses for “Preaddiction” severity index

K Blum, D Han, A Bowirrat, BW Downs… - Journal of Personalized …, 2022 - mdpi.com
Since 1990, when our laboratory published the association of the DRD2 Taq A1 allele and
severe alcoholism in JAMA, there has been an explosion of genetic candidate association …

Why haven't we solved the addiction crisis?

K Blum, A Bowirrat, LL Gomez, BW Downs… - Journal of the …, 2022 - Elsevier
The current addiction crisis has destroyed a multitude of lives, leaving millions of fatalities
worldwide in its wake. At the same time, various governmental agencies dedicated to …

[HTML][HTML] Summary document research on RDS anti-addiction modeling: annotated bibliography

K Blum, D Baron, T McLaughlin… - Journal of addiction …, 2024 - ncbi.nlm.nih.gov
Annotated bibliography of genetic addiction risk severity (GARS) publications, pro-dopamine
regulation in nutraceuticals (KB220 nutraceutical variants), and policy documents. Further …

[HTML][HTML] Evidence for the DRD2 gene as a determinant of Reward Deficiency Syndrome (RDS)

K Blum, A Bowirrat, I Elman, D Baron… - Clinical and …, 2023 - ncbi.nlm.nih.gov
Since 1990, published addiction psychiatry articles have exceeded 11,495. Several from
Blum et al. showed the clinical relevance of the Genetic Addiction Risk Severity (GARS) test …

[HTML][HTML] Genetic addiction risk severity assessment identifies polymorphic reward genes as antecedents to reward deficiency syndrome (RDS) hypodopaminergia's …

CA Dennen, K Blum, A Bowirrat, PK Thanos… - Journal of Personalized …, 2022 - mdpi.com
This case series presents the novel genetic addiction risk score (GARS), which shows a high
prevalence of polymorphic risk alleles of reward genes in a nuclear family with multiple …