[HTML][HTML] Unraveling Adipose Tissue Dysfunction: Molecular Mechanisms, Novel Biomarkers, and Therapeutic Targets for Liver Fat Deposition

M Lopez-Yus, C Hörndler, S Borlan, V Bernal-Monterde… - Cells, 2024 - mdpi.com
Adipose tissue (AT), once considered a mere fat storage organ, is now recognized as a
dynamic and complex entity crucial for regulating human physiology, including metabolic …

[HTML][HTML] Clinically Effective Molecules of Natural Origin for Obesity Prevention or Treatment

GM Hidalgo-Lozada, A Villarruel-López… - International Journal of …, 2024 - mdpi.com
The prevalence and incidence of obesity and the comorbidities linked to it are increasing
worldwide. Current therapies for obesity and associated pathologies have proven to cause a …

Combination of Gold Nanoparticles with Carnitine Attenuates Brain Damage in an Obesity Animal Model

LE da Silva, JS Abel, G Tartari, MR da Silva… - Molecular …, 2024 - Springer
Obesity causes inflammation in the adipose tissue and can affect the central nervous
system, leading to oxidative stress and mitochondrial dysfunction. Therefore, it becomes …

[HTML][HTML] Rare Variants of Obesity-Associated Genes in Young Adults with Abdominal Obesity

A Bairqdar, E Shakhtshneider, D Ivanoshchuk… - Journal of Personalized …, 2023 - mdpi.com
The increase in the prevalence of overweight, obesity and associated diseases is a serious
problem. The aim of the study was to identify rare variants in obesity-associated genes in …

[HTML][HTML] Anti-adipogenic and anti-obesity effects of morroniside in vitro and in vivo

KI Oh, E Lim, LP Uprety, J Jeong, H Jeong… - Biomedicine & …, 2024 - Elsevier
Obesity is a multifaceted medical condition characterized by the pathological accumulation
of excessive lipids in the body. We investigated the effects of morroniside, a bioactive …

[HTML][HTML] New Mediators in the Crosstalk between Different Adipose Tissues

A Gómez-Hernández, N de Las Heras… - International Journal of …, 2024 - mdpi.com
Adipose tissue is a multifunctional organ that regulates many physiological processes such
as energy homeostasis, nutrition, the regulation of insulin sensitivity, body temperature, and …

[HTML][HTML] Anti-Obesity Effect and Signaling Mechanism of Potassium Poly-γ-Glutamate Produced by Bacillus subtilis Chungkookjang in High-Fat Diet-Induced Obese …

SH Lee, J Choi, JY Park, HR Kim, M Shim, K Im… - Nutrients, 2024 - mdpi.com
The purpose of this work was to examine the effects of potassium poly-γ-glutamate (PGA-K)
on mice fed a high-fat diet consisting of 60% of total calories for 12 weeks. PGA-K …

[HTML][HTML] Novel role of Quercetin in ameliorating metabolic syndrome via VDR mediated activation of adiponectin/AdipoR2 signaling

NGS Gowda, VD Shiragannavar… - … and Biophysics Reports, 2024 - Elsevier
A sedentary lifestyle and physical inactivity leads to metabolic syndrome-associated
comorbidities involving abdominal obesity, type 2 diabetes, hyperlipidaemia associated …

[HTML][HTML] 7-MEGA™ inhibits adipogenesis in 3T3-L1 adipocytes and suppresses obesity in high-fat-diet-induced obese C57BL/6 mice

YS Won, SG Bak, N Chandimali… - Lipids in Health …, 2024 - lipidworld.biomedcentral.com
Overweight, often known as obesity, is the abnormal and excessive accumulation of fat that
exposes the health of a person at risk by increasing the likelihood that they may experience …

[HTML][HTML] Metabolic Disorders, the Microbiome as an Endocrine Organ, and Their Relations with Obesity: A Literature Review

S Ispas, LA Tuta, M Botnarciuc, V Ispas… - Journal of Personalized …, 2023 - mdpi.com
The etiology of metabolic disorders, such as obesity, has been predominantly associated
with the gut microbiota, which is acknowledged as an endocrine organ that plays a crucial …