[HTML][HTML] Peptide-based agents for cancer treatment: current applications and future directions
Peptide-based strategies have received an enormous amount of attention because of their
specificity and applicability. Their specificity and tumor-targeting ability are applied to …
specificity and applicability. Their specificity and tumor-targeting ability are applied to …
[HTML][HTML] Recent advances in cancer vaccines: challenges, achievements, and futuristic prospects
Cancer is a chronic disease, and it can be lethal due to limited therapeutic options. The
conventional treatment options for cancer have numerous challenges, such as a low blood …
conventional treatment options for cancer have numerous challenges, such as a low blood …
[HTML][HTML] TGFβ-derived immune modulatory vaccine: targeting the immunosuppressive and fibrotic tumor microenvironment in a murine model of pancreatic cancer
M Perez-Penco, SE Weis-Banke, A Schina… - … for immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Background Pancreatic ductal adenocarcinoma (PDAC) is associated with very poor
survival, making it the third and fourth leading cause of all cancer-related deaths in the USA …
survival, making it the third and fourth leading cause of all cancer-related deaths in the USA …
Targeting survivin for cancer therapy: Strategies, small molecule inhibitors and vaccine based therapeutics in development
SK Kondapuram, HK Ramachandran, H Arya… - Life Sciences, 2023 - Elsevier
Survivin is a member of the family of inhibitors of apoptosis proteins (IAPs). It is involved in
the normal mitotic process and acts as an anti-apoptotic molecule. While terminally …
the normal mitotic process and acts as an anti-apoptotic molecule. While terminally …
Targeted therapies against breast cancer: Clinical perspectives, obstacles and new opportunities
Breast cancer is a multifaceted, heterogeneous disease that manifests in the mammary
gland. According to the WHO, more than 2.3 million cases are diagnosed each year, making …
gland. According to the WHO, more than 2.3 million cases are diagnosed each year, making …
[HTML][HTML] Cancer testis antigen subfamilies: Attractive targets for therapeutic vaccine
S Ren, Z Zhang, M Li, D Wang… - International …, 2023 - spandidos-publications.com
Cancer‑testis antigen (CTA) is a well‑accepted optimal target library for cancer diagnosis
and treatment. Most CTAs are located on the X chromosome and aggregate into large gene …
and treatment. Most CTAs are located on the X chromosome and aggregate into large gene …
[HTML][HTML] mRNA vaccine in gastrointestinal tumors: Immunomodulatory effects and immunotherapy
A Zhang, Q Ji, X Sheng, H Wu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Gastrointestinal tumors remain a significant healthcare burden worldwide, necessitating the
development of innovative therapeutic strategies. mRNA vaccines have emerged as a …
development of innovative therapeutic strategies. mRNA vaccines have emerged as a …
Engineering nanomaterials for glioblastoma nanovaccination
Glioblastoma is a lethal brain cancer with treatment resistance stemming from its interactions
with the surrounding microenvironment and obstacles such as the blood–brain barrier …
with the surrounding microenvironment and obstacles such as the blood–brain barrier …
Targeting tumor heterogeneity with neoantigen-based cancer vaccines
Neoantigen-based cancer vaccines have emerged as a promising immunotherapeutic
approach to treat cancer. Nevertheless, the high degree of heterogeneity in tumors poses a …
approach to treat cancer. Nevertheless, the high degree of heterogeneity in tumors poses a …
[HTML][HTML] Overcoming suppressive tumor microenvironment by vaccines in solid tumor
Conventional vaccines are widely used to boost human natural ability to defend against
foreign invaders, such as bacteria and viruses. Recently, therapeutic cancer vaccines …
foreign invaders, such as bacteria and viruses. Recently, therapeutic cancer vaccines …