Human papillomavirus vaccines: current status and future prospects

SM Garland, JS Smith - Drugs, 2010 - Springer
Worldwide, cervical cancer is the second most common cancer of women. Less-developed
countries bear the greatest burden in terms of morbidity and mortality, largely due to the lack …

The role of co-factors in the progression from human papillomavirus infection to cervical cancer

P Luhn, J Walker, M Schiffman, RE Zuna, ST Dunn… - Gynecologic …, 2013 - Elsevier
OBJECTIVE: Co-factors for cervical cancer, including oral contraceptive (OC) use, smoking
and multiparity have been identified; however, the stage at which they act in cervical …

An evaluation of novel, lower-cost molecular screening tests for human papillomavirus in rural China

FH Zhao, J Jeronimo, YL Qiao, J Schweizer… - Cancer prevention …, 2013 - AACR
New, lower-cost tests that target high-risk human papillomavirus (HR-HPV) have been
developed for cervical cancer screening in lower-resource settings but large, population …

CIN III lesions and regression: retrospective analysis of 635 cases

M Motamedi, G Böhmer, HH Neumann… - BMC infectious …, 2015 - Springer
Background The rate of spontaneous regression in CIN III lesions is controversial. Whereas
some studies have reported high regression rates of up to 38% after prolonged biopsy …

HLA-Cw group 1 ligands for KIR increase susceptibility to invasive cervical cancer

MP Martin, IB Borecki, Z Zhang, L Nguyen, D Ma… - Immunogenetics, 2010 - Springer
Inherited genetic polymorphisms within immune response genes have been shown to
associate with risk of invasive cervical cancer (ICC) and its immediate precursor, cervical …

[PDF][PDF] Persistent high-risk human papillomavirus (HPV) infections as surrogate endpoints of progressive cervical disease. Potential new endpoint for efficacy studies …

K Syrjänen - Eur. J. Gynaec. Oncol.-ISSN, 2011 - article.imrpress.com
Recent data indicate that persistent HR-HPV infections represent a significantly increased
risk of developing incident high-grade CIN and cervical cancer. Accordingly, 6-month (6M+) …

Three-year risk of cervical precancer and cancer after the detection of low-risk human papillomavirus genotypes targeted by a commercial test

PE Castle, WC Hunt, E Langsfeld… - Obstetrics & …, 2014 - journals.lww.com
OBJECTIVE: To investigate the risk of cervical precancer and cancer associated with
detection of human papillomavirus (HPV) 6, 11, and 42. METHODS: We used data from the …

Co-factors of high-risk human papillomavirus infections display unique profiles in incident CIN1, CIN2 and CIN3

K Syrjänen, I Shabalova, P Naud… - … journal of STD & …, 2011 - journals.sagepub.com
In addition to oncogenic 'high-risk'human papillomaviruses (HR-HPV), several co-factors are
needed in cervical carcinogenesis, but it is poorly understood whether these HPV co-factors …

Scoring system and management algorithm assessing the role of survivin expression in predicting progressivity of HPV infections in precancerous cervical lesions

J Indarti, MF Aziz, B Suryawati… - Asian Pacific Journal of …, 2013 - journal.waocp.org
Background: To identify the risk factors and assess the role of survivin in predicting
progessivity precancerouscervical lesions. Materials and Methods: This case-control study …

[PDF][PDF] Covariates of high-risk human papillomavirus (HPV) infections are distinct for incident CIN1, CIN2 and CIN3 as disclosed by competing-risks regression models

K Syrjänen, I Shabalova, L Sarian, P Naud… - Eur. J. Gynaec. Oncol …, 2012 - researchgate.net
Background: In addition to the oncogenic human papillomavirus (HPV), several cofactors
are needed in cervical carcinogenesis, but whether the HPV covariates associated with …