Supersaturated Drug Delivery System of Oxyberberine Based on Cyclodextrin Nanoaggregates: Preparation, Characterization, and in vivo Application

Z Huang, S Zhang, Z Qin, G Ai, M Li… - International Journal …, 2024 - Taylor & Francis
Propose Oxyberberine (OBB), one of the main metabolites of berberine derived from
intestinal and erythrocyte metabolism, exhibits appreciable anti-hyperuricemic activity …

[HTML][HTML] SH-Alb inhibits phenotype remodeling of pro-fibrotic macrophage to attenuate liver fibrosis through SIRT3-SOD2 axis

N Wu, S Ma, H Ding, H Cao, T Liu, M Tian, Q Liu… - Biomedicine & …, 2024 - Elsevier
Albumin has a variety of biological functions, such as immunomodulatory and antioxidant
activity, which depends largely on its thiol activity. However, in clinical trials, the treatment of …

Altered accumulation of hepatic mitochondrial antioxidant proteins with age and environmental heat stress

JL Haak, KC Kregel… - Journal of Applied …, 2023 - journals.physiology.org
Aging impairs overall physiological function, particularly the response to environmental
stressors. Repeated heat stress elevates reactive oxygen species and macromolecular …