YB‐1 protein: functions and regulation
DN Lyabin, IA Eliseeva… - Wiley Interdisciplinary …, 2014 - Wiley Online Library
The Y‐box binding protein 1 (YB‐1, YBX1) is a member of the family of DNA‐and RNA‐
binding proteins with an evolutionarily ancient and conserved cold shock domain. It falls into …
binding proteins with an evolutionarily ancient and conserved cold shock domain. It falls into …
Y-box-binding protein 1 (YB-1) and its functions
IA Eliseeva, ER Kim, SG Guryanov… - Biochemistry …, 2011 - Springer
This review describes the structure and functions of Y-box binding protein 1 (YB-1) and its
homologs. Interactions of YB-1 with DNA, mRNAs, and proteins are considered. Data on the …
homologs. Interactions of YB-1 with DNA, mRNAs, and proteins are considered. Data on the …
Loss of super-enhancer-regulated circRNA Nfix induces cardiac regeneration after myocardial infarction in adult mice
S Huang, X Li, H Zheng, X Si, B Li, G Wei, C Li… - Circulation, 2019 - Am Heart Assoc
Background: circRNAs (circular RNAs) are emerging as powerful regulators of cardiac
development and disease, but their roles in cardiac regeneration are still unknown. This …
development and disease, but their roles in cardiac regeneration are still unknown. This …
[HTML][HTML] Reducing hypothalamic stem cell senescence protects against aging-associated physiological decline
Age-dependent loss of hypothalamic neural stem cells (htNSCs) is important for the
pathological consequences of aging; however, it is unclear what drives the senescence of …
pathological consequences of aging; however, it is unclear what drives the senescence of …
A comprehensive review of the functions of YB-1 in cancer stemness, metastasis and drug resistance
The Y Box binding protein 1 (YB-1) is a member of the highly conserved Cold Shock Domain
protein family with multifunctional properties both in the cytoplasm and inside the nucleus …
protein family with multifunctional properties both in the cytoplasm and inside the nucleus …
[HTML][HTML] Y-box binding proteins in mRNP assembly, translation, and stability control
D Mordovkina, DN Lyabin, EA Smolin, EM Sogorina… - Biomolecules, 2020 - mdpi.com
Y-box binding proteins (YB proteins) are DNA/RNA-binding proteins belonging to a large
family of proteins with the cold shock domain. Functionally, these proteins are known to be …
family of proteins with the cold shock domain. Functionally, these proteins are known to be …
Identification and characterization of lin-28 homolog B (LIN28B) in human hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide.
Several studies have identified signature gene sets that may be useful as potential …
Several studies have identified signature gene sets that may be useful as potential …
[HTML][HTML] Tight junctions and the regulation of gene expression
MS Balda, K Matter - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2009 - Elsevier
Cell adhesion is a key regulator of cell differentiation. Cell interactions with neighboring cells
and the extracellular matrix regulate gene expression, cell proliferation, polarity and …
and the extracellular matrix regulate gene expression, cell proliferation, polarity and …
YB-1 is a positive regulator of KLF5 transcription factor in basal-like breast cancer
D Jiang, T Qiu, J Peng, S Li, Tala, W Ren… - Cell Death & …, 2022 - nature.com
Y-box binding protein 1 (YB-1) is a well-known oncogene highly expressed in various
cancers, including basal-like breast cancer (BLBC). Beyond its role as a transcription factor …
cancers, including basal-like breast cancer (BLBC). Beyond its role as a transcription factor …
Akt phosphorylates the Y-box binding protein 1 at Ser102 located in the cold shock domain and affects the anchorage-independent growth of breast cancer cells
BW Sutherland, J Kucab, J Wu, C Lee, MCU Cheang… - Oncogene, 2005 - nature.com
Akt/PKB is a serine/threonine kinase that promotes tumor cell growth by phosphorylating
transcription factors and cell cycle proteins. There is particular interest in finding tumor …
transcription factors and cell cycle proteins. There is particular interest in finding tumor …