Immune mechanisms linking metabolic injury to inflammation and fibrosis in fatty liver disease–novel insights into cellular communication circuits

M Peiseler, R Schwabe, J Hampe, P Kubes… - Journal of …, 2022 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease and is
emerging as the leading cause of cirrhosis, liver transplantation and hepatocellular …

[HTML][HTML] Role of B cells as antigen presenting cells

I Rastogi, D Jeon, JE Moseman, A Muralidhar… - Frontiers in …, 2022 - frontiersin.org
B cells have been long studied for their role and function in the humoral immune system.
Apart from generating antibodies and an antibody-mediated memory response against …

[HTML][HTML] Pan-cancer single-cell analysis reveals the heterogeneity and plasticity of cancer-associated fibroblasts in the tumor microenvironment

H Luo, X Xia, LB Huang, H An, M Cao, GD Kim… - Nature …, 2022 - nature.com
Cancer-associated fibroblasts (CAFs) are the predominant components of the tumor
microenvironment (TME) and influence cancer hallmarks, but without systematic …

B cells in autoimmune and neurodegenerative central nervous system diseases

JJ Sabatino Jr, AK Pröbstel, SS Zamvil - Nature Reviews Neuroscience, 2019 - nature.com
B cells are essential components of the adaptive immune system and have important roles
in the pathogenesis of several central nervous system (CNS) diseases. Besides producing …

[HTML][HTML] Single-cell epigenomic landscape of peripheral immune cells reveals establishment of trained immunity in individuals convalescing from COVID-19

M You, L Chen, D Zhang, P Zhao, Z Chen, EQ Qin… - Nature cell …, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection often causes
severe complications and even death. However, asymptomatic infection has also been …

[HTML][HTML] NF-κB in inflammation and renal diseases

H Zhang, SC Sun - Cell & bioscience, 2015 - Springer
Nuclear factor κB (NF-κB) is a family of inducible transcription factors that plays a vital role in
different aspects of immune responses. NF-κB is normally sequestered in the cytoplasm as …

[HTML][HTML] Physiology, pathology and regeneration of salivary glands

C Porcheri, TA Mitsiadis - Cells, 2019 - mdpi.com
Salivary glands are essential structures in the oral cavity. A variety of diseases, such as
cancer, autoimmune diseases, infections and physical traumas, can alter the functionality of …

Sjogren's syndrome: An update on disease pathogenesis, clinical manifestations and treatment

FB Vivino, VY Bunya… - Clinical …, 2019 - pubmed.ncbi.nlm.nih.gov
Sjogren's syndrome: An update on disease pathogenesis, clinical manifestations and treatment
Sjogren's syndrome: An update on disease pathogenesis, clinical manifestations and treatment …

B lymphocytes: how they develop and function

TW LeBien, TF Tedder - Blood, The Journal of the American …, 2008 - ashpublications.org
The discovery that lymphocyte subpopulations participate in distinct components of the
immune response focused attention onto the origins and function of lymphocytes more than …

The two NF-κB activation pathways and their role in innate and adaptive immunity

G Bonizzi, M Karin - Trends in immunology, 2004 - cell.com
NF-κB was first described as a B-cell-specific transcription factor that binds the κB site in the
Ig κ light chain enhancer. Soon after, NF-κB activity was found to be inducible in all cell types …