Anticancer potential of lichens' secondary metabolites

Z Solárová, A Liskova, M Samec, P Kubatka… - Biomolecules, 2020 - mdpi.com
Lichens produce different classes of phenolic compounds, including anthraquinones,
xanthones, dibenzofuranes, depsides and depsidones. Many of them have revealed …

Enantioselective activity of usnic acid: A comprehensive review and future perspectives

A Galanty, P Paśko, I Podolak - Phytochemistry Reviews, 2019 - Springer
This review is focused on the comparison of the biological and pharmacological activities of
usnic acid enantiomers. Most of the available data refer to (+)-usnic acid, while the left …

Shape-controlled magnetic mesoporous silica nanoparticles for magnetically-mediated suicide gene therapy of hepatocellular carcinoma

Z Wang, Z Chang, M Lu, D Shao, J Yue, D Yang… - Biomaterials, 2018 - Elsevier
Magnetic nanoparticles (NPs) have emerged as a promising tool for suicide gene therapy.
However, the separate delivery of the suicide gene and prodrug in current systems limits …

Secondary metabolites from cetrarioid lichens: Chemotaxonomy, biological activities and pharmaceutical potential

M Xu, S Heidmarsson, ES Olafsdottir, R Buonfiglio… - Phytomedicine, 2016 - Elsevier
Background Lichens, as a symbiotic association of photobionts and mycobionts, display an
unmatched environmental adaptability and a great chemical diversity. As an important …

Bioactive lichen secondary metabolites and their presence in species from Chile

E Poulsen-Silva, F Gordillo-Fuenzalida, C Atala… - Metabolites, 2023 - mdpi.com
Lichens are symbiotic organisms composed of at least one fungal and one algal species.
They are found in different environments around the world, even in the poles and deserts …

Green synthesis of carrier-free curcumin nanodrugs for light-activated breast cancer photodynamic therapy

M Sun, Y Zhang, Y He, M Xiong, H Huang, S Pei… - Colloids and Surfaces B …, 2019 - Elsevier
Photodynamic therapy (PDT) is a promising procedure for breast cancer therapy. Curcumin
(Cur), a hydrophobic polyphenol derived from the spice turmeric, has been considered as a …

The genus Usnea: A potent phytomedicine with multifarious ethnobotany, phytochemistry and pharmacology

BS Paliya, R Bajpai, V Jadaun, J Kumar, S Kumar… - RSC …, 2016 - pubs.rsc.org
The genus Usnea Adans.(Parmeliaceae; lichenized Ascomycetes) is a typical group of
mostly pale grayish-green fruticoselichens that grow as leafless mini-shrubs. More than 360 …

Anticancer effects of ginsenoside Rk3 on non-small cell lung cancer cells: in vitro and in vivo

Z Duan, J Deng, Y Dong, C Zhu, W Li, D Fan - Food & function, 2017 - pubs.rsc.org
Ginsenoside Rk3 (Rk3) is present in the roots of processed Panax notoginseng herbs and it
exerts anti-platelet aggregation, pro-immunogenic and cardioprotective effects. However …

Changes in apoptosis-related gene expression profiles in cancer cell lines exposed to usnic acid lichen secondary metabolite

AB Dincsoy, DC Duman - Turkish Journal of Biology, 2017 - journals.tubitak.gov.tr
The presence of uninhibited side effects of cancer drugs often used in cancer treatment has
stimulated the search for alternative therapeutic approaches. Therefore, anticarcinogenic …

The role of usnic acid-induced apoptosis and autophagy in hepatocellular carcinoma

B Yurdacan, U Egeli, GG Eskiler… - Human & …, 2019 - journals.sagepub.com
Usnic acid (UA) is a multifunctional bioactive lichen secondary metabolite with potential anti-
cancer properties. Although the promising therapeutic effects of UA have been investigated …