[HTML][HTML] Management of non-response and loss of response to anti-tumor necrosis factor therapy in inflammatory bowel disease

J Marsal, M Barreiro-de Acosta, I Blumenstein… - Frontiers in …, 2022 - frontiersin.org
Anti-tumor necrosis factor (anti-TNF) therapy has been successfully used as first-line
biologic treatment for moderate-to-severe inflammatory bowel disease (IBD), in both “step …

[HTML][HTML] Increasing Access to Effective systemic treatments in patients with moderate-to-severe psoriasis: Narrative Review

G Girolomoni, L Savage, P Gisondi, Å Svensson… - Dermatology and …, 2023 - Springer
Psoriasis is a chronic, immune-mediated inflammatory disease with a worldwide prevalence
ranging between 0.51 and 11.43%. It results in a large clinical and social burden, with …

[HTML][HTML] Improving global healthcare and reducing costs using second-generation artificial intelligence-based digital pills: a market disruptor

Y Ilan - International Journal of Environmental Research and …, 2021 - mdpi.com
Background and Aims: Improving global health requires making current and future drugs
more effective and affordable. While healthcare systems around the world are faced with …

[HTML][HTML] Association between environmental chemicals co-exposure and peripheral blood immune-inflammatory indicators

Y Liu, Z Zhang, D Han, Y Zhao, X Yan… - Frontiers in Public …, 2022 - frontiersin.org
Chronic inflammation is closely related to chronic inflammatory diseases, autoimmune
diseases and cancer. Few studies have evaluated the effects of exposure to multiple …

Current evidence on the use of the adalimumab biosimilar SB5 (ImraldiTM): a multidisciplinary perspective

JP Gisbert, K Gaffney, D Young… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction This review provides an overview of data from trials and real-world studies
available for SB5 (ImraldiTM) across three main therapeutic areas: rheumatology …

Assessing biomarkers in viral infection

ES Mayne, JA George, S Louw - … of Omic Techniques to Identify New …, 2023 - Springer
Current biomarkers to assess the risk of complications of both acute and chronic viral
infection are suboptimal. Prevalent viral infections like human immunodeficiency virus (HIV) …

[HTML][HTML] The PROPER Study: A 48-Week, Pan-European, Real-World Study of Biosimilar SB5 Following Transition from Reference Adalimumab in Patients with …

U Müller-Ladner, A Dignass, K Gaffney, D Jadon… - BioDrugs, 2023 - Springer
Background The non-interventional PROPER study generated real-world evidence on
clinical outcomes following transition in routine practice from reference adalimumab to the …

Real‐world outcomes of switching from adalimumab originator to adalimumab biosimilar in patients with inflammatory bowel disease: The ADA‐SWITCH study

MJ Casanova, Ó Nantes, P Varela… - Alimentary …, 2023 - Wiley Online Library
Summary Background and Aims Data on the outcomes after switching from adalimumab
(ADA) originator to ADA biosimilar are limited. The aim was to compare the treatment …

Patient-reported outcomes in rheumatoid arthritis: a key consideration for evaluating biosimilar uptake?

G Horta-Baas - Patient related outcome measures, 2022 - Taylor & Francis
Purpose This review aims to provide an overview of the impact of TNFis biosimilars, with
marketing authorization, in patient-reported outcome measures (PROMs) scores and …

Comparative efficacy and safety of etanercept biosimilars in comparison with etanercept in patients with rheumatoid arthritis who have insufficient response to …

YH Lee, GG Song - International Journal of Clinical …, 2021 - search.proquest.com
Objective: We aimed to assess the relative efficacy and safety of etanercept biosimilars and
etanercept originators in patients with active rheumatoid arthritis (RA) who showed an …