[HTML][HTML] Impact of the timeliness of antibiotic therapy on the outcome of patients with sepsis and septic shock

SA Asner, F Desgranges, IT Schrijver, T Calandra - Journal of Infection, 2021 - Elsevier
Objectives To review the impact of the timeliness of antibiotic therapy on the outcome of
patients with sepsis or septic shock. Methods We searched MEDLINE, EMBASE, the …

A systematic review of the effect of delayed appropriate antibiotic treatment on the outcomes of patients with severe bacterial infections

EJ Zasowski, M Bassetti, F Blasi, H Goossens, J Rello… - Chest, 2020 - Elsevier
Background Patients with severe bacterial infections often experience delay in receiving
appropriate treatment. Consolidated evidence of the impact of delayed appropriate …

Time from admission to initiation of surgery for source control is a critical determinant of survival in patients with gastrointestinal perforation with associated septic …

T Azuhata, K Kinoshita, D Kawano, T Komatsu… - Critical Care, 2014 - Springer
Introduction We developed a protocol to initiate surgical source control immediately after
admission (early source control) and perform initial resuscitation using early goal-directed …

An alternate pathophysiologic paradigm of sepsis and septic shock: implications for optimizing antimicrobial therapy

A Kumar - Virulence, 2014 - Taylor & Francis
The advent of modern antimicrobial therapy following the discovery of penicillin during the
1940s yielded remarkable improvements in case fatality rate of serious infections including …

Optimizing antimicrobial therapy of sepsis and septic shock: focus on antibiotic combination therapy

G Vazquez-Grande, A Kumar - Seminars in respiratory and …, 2015 - thieme-connect.com
There has been little improvement in septic shock mortality in the past 70 years, despite ever
more broad-spectrum and potent antimicrobials. In the past, resuscitative elements have …

Prevalence of multidrug-resistant gram-negative bacteria among nursing home residents: a systematic review and meta-analysis

S Aliyu, A Smaldone, E Larson - American journal of infection control, 2017 - Elsevier
Background Multidrug-resistant gram-negative bacteria (MDR-GNB) are associated with an
increasing proportion of infections among nursing home (NH) residents. The objective of this …

Accuracy of point of care ultrasound to identify the source of infection in septic patients: a prospective study

F Cortellaro, L Ferrari, F Molteni, P Aseni… - Internal and emergency …, 2017 - Springer
Sepsis is a rapidly evolving disease with a high mortality rate. The early identification of
sepsis and the implementation of early evidence-based therapies have been recognized to …

The increasing application of multiplex nucleic acid detection tests to the diagnosis of syndromic infections

J Gray, LJ Coupland - Epidemiology & Infection, 2014 - cambridge.org
On 14 January 2013, the US Food and Drug Administration (FDA) announced permission for
a multiplex nucleic acid test, the xTAG® Gastrointestinal Pathogen Panel (GPP)(Luminex …

Antimicrobial use in companion animals: Assessing veterinarians' prescription patterns through the first national survey in Chile

N Galarce, G Arriagada, F Sánchez, V Venegas… - Animals, 2021 - mdpi.com
Simple Summary Antimicrobial resistance is a growing global health issue for both animal
and public health agencies. One major driver for the development and spread of …

Antimicrobial and resource utilization with T2 magnetic resonance for rapid diagnosis of bloodstream infections: systematic review with meta-analysis of controlled …

M Giannella, GA Pankey, R Pascale… - Expert Review of …, 2021 - Taylor & Francis
Objectives: To compare antimicrobial and resource utilization with T2 Magnetic Resonance
(T2MR) versus blood culture (BC) in patients with suspected bloodstream infection …