Glomerulonephritis (GN) comprises a group of immune-mediated kidney diseases affecting
glomeruli and the tubulointerstitium. Glomerular crescent formation is a histopathological …

Psoriasis is a chronic autoimmune inflammatory disease characterized by erroneous
metabolism of keratinocytes. The development of psoriasis is closely related to abnormal …

Glomerulonephritis is a group of immune-mediated diseases that cause inflammation within
the glomerulus and adjacent compartments of the kidney and is a major cause of end-stage …

SARS-CoV-2 has caused an estimated 7 million deaths worldwide to date. A secreted SARS-
CoV-2 accessory protein, known as open reading frame 8 (ORF8), elicits inflammatory …

Depression is a severe mental disorder that disrupts mood and social behavior and is one of
the most common neuropsychological symptoms of other somatic diseases. During the study …

Background Tripartite motif-containing protein 33, a member of the TRIM E3 ligase family, is
shown to be involved in tumorigenesis, cell proliferation and inflammation. Alteration of …

In recent studies, primary aldosteronism (PA) has been reported as the most common
etiology for secondary hypertension of endocrine origin, accounting for approximately 10 …

Ischemia–reperfusion injury (IRI) is one of the major causes of acute kidney injury (AKI), and
experimental work has revealed detailed insight into the inflammatory response in the …

Background Patients with severe psoriasis are prone to deterioration of renal function.
Whether biologics with potent anti-inflammatory action can prevent deterioration of renal …

Gammaherpesviruses, such as human Epstein-Barr virus (EBV) and murine
gammaherpesvirus 68 (MHV68), are species-specific, ubiquitous pathogens that are …