Neurons in the hypothalamic arcuate nucleus (ARC) that express agouti‐related peptide
(AgRP) govern a critical aspect of survival: the drive to eat. Equally important to survival is …

Prolactin is a protein hormone of the anterior pituitary gland that was originally named for its
ability to promote lactation in response to the suckling stimulus of hungry young mammals …

The locus coeruleus (LC) is a small nucleus in the pons from which ascending and
descending projections innervate major parts of the central nervous system. Its major …

The gastrointestinal peptide hormone ghrelin stimulates appetite in rodents and humans via
hypothalamic actions. We discovered expression of ghrelin in a previously uncharacterized …

Melatonin, the major hormone produced by the pineal gland, displays characteristic daily
and seasonal patterns of secretion. These robust and predictable rhythms in circulating …

Neuropeptide Y (NPY) and the endogenous melanocortin receptor antagonist, agouti gene-
related protein (AGRP), coexist in the arcuate nucleus, and both exert orexigenic effects. The …

Recently published work and emerging research efforts have suggested that the olfactory
system is intimately linked with the endocrine systems that regulate or modify energy …

The third edition of this monograph continues to have the goal of providing an overview of
current thought about the spinal cord mechanisms that are responsible for sensory …

Neuropeptide Y (NPY), a putative neurotransmitter abundant in the brain, has recently been
shown to act within the hypothalamus, inducing a powerful eating response and a specific …

Cells in the lateral hypothalamus and in the arcuate nucleus play prominent roles in the
central control of food intake; however, a neurochemical link connecting these potential …