The primary coverage of this paper is to investigate the molecular interaction of JAK2
inhibitor, fedratinib (FED) with BSA/HAG proteins through multispectral approaches and …

The protein-ligand binding frequently occurs in living organisms and plays a crucial role in
the execution of the functions of proteins and drugs. It is also an indispensable part of drug …

Enzymatic browning is of concern as it can affect food safety and quality. In this study, an
effective and safe tyrosinase inhibitor and anti-browning agent, methyl 4-pyridyl ketone …

Indole-based bis-acylhydrazone compounds can inhibit the activity of α-glucosidase and
control the concentration of blood glucose. In this paper, the characteristics of three indole …

Plasma protein binding of therapeutic bioactive materials, especially anticancer compounds
can play an important role in their pharmacokinetics and pharmacodynamics. Human α-1 …

Glucose transporters GLUT1 belong to the major facilitator superfamily and are essential to
human glucose uptake. The overexpression of GLUT1 in tumor cells designates it as a …

Dacomitinib is a highly selective second-generation tyrosine kinase inhibitor that can
irreversibly bind to tyrosine kinase and is mainly used in the treatment of lung cancer. The …