Mucosal surfaces in the lung interface with the outside environment for breathing purposes,
but also provide the first line of defense against invading pathogens. The intricate balance of …

The primary objective of this thesis is to establish the functional roles of β-catenin and
glycogen synthase kinase-3 (GSK-3) in the pathological processes that underpin chronic …

University of Groningen Glycogen synthase kinase-3 (GSK-3) and β-catenin Baarsma, Hoeke
Abele Page 1 University of Groningen Glycogen synthase kinase-3 (GSK-3) and β-catenin …

Introduction: Idiopathic pulmonary fibrosis (IPF) is a fatal disease characterized by an
aberrant interstitial deposition of collagen in the lung parenchyma, leading to progressive …

Although AMP-activated protein kinase (AMPK) is involved in regulating carbohydrate and
lipid metabolism, activated AMPK also plays an anti-inflammatory role in many cell …

[eng] INTRODUCTION: In 1966, Rett syndrome (RTT, OMIM# 312750) was for the first time
described as a clinical issue by Dr. Andreas Rett, an Austrian pediatrician. He has observed …

A agmatina é uma amina catiônica endógena cuja ação antidepressiva é reportada em
diversos estudos nos últimos anos. O presente estudo investigou o efeito do tratamento …

Pulmonary inflammation in acute and chronic disease is often accompanied by skeletal
muscle atrophy. Glycogen synthase kinase‐3 (GSK‐3) has been implicated in the regulation …

Chronisch obstructief longlijden of chronic obstructive pulmonary disease (COPD) is een
ziekte die meestal veroorzaakt wordt sigarettenrook. De ziekte wordt gekarakteriseerd door …

Leukemia is a clonal neoplastic disorder that results from the acquisition of genetic lesions
in hematopoietic stem and progenitor cells (HSPCs). Leukemia stem cells (LSCs), a …