Flavonols in action: Targeting oxidative stress and neuroinflammation in major depressive disorder

M Jazvinšćak Jembrek, N Oršolić, D Karlović… - International journal of …, 2023 - mdpi.com
Major depressive disorder is one of the most common mental illnesses that highly impairs
quality of life. Pharmacological interventions are mainly focused on altered monoamine …

Clinical correlates and thyroid hormones of metabolic syndrome in first-episode and drug-naïve major depressive disorder outpatients with and without hyperglycemia …

S Zheng, Z Wang, L Yang, X Zhang - BMC psychiatry, 2023 - Springer
Hyperglycemia and metabolic syndrome (MetS) are common in patients with major
depressive disorder (MDD). This study aimed to explore the prevalence and clinical factors …

Serum neuroactive metabolites of the tryptophan pathway in patients with acute phase of affective disorders

Y Li, L Wang, J Huang, P Zhang, Y Zhou, J Tong… - Frontiers in …, 2024 - frontiersin.org
Background Many studies showed disrupted tryptophan metabolism in patients with affective
disorders. The aims of this study were to explore the differences in the metabolites of …

[HTML][HTML] Increased Parenchymal Macrophages are associated with decreased Tyrosine Hydroxylase mRNA levels in the Substantia Nigra of people with …

G Mendez-Victoriano, Y Zhu, F Middleton, PT Massa… - Psychiatry …, 2024 - Elsevier
Increased activation of inflammatory macrophages and altered expression of dopamine
markers are found in the midbrains of people with schizophrenia (SZ). The relationship of …