Mechanistic understanding of protein Corona formation around nanoparticles: old puzzles and new insights
K Nienhaus, GU Nienhaus - Small, 2023 - Wiley Online Library
Although a wide variety of nanoparticles (NPs) have been engineered for use as disease
markers or drug delivery agents, the number of nanomedicines in clinical use has hitherto …
markers or drug delivery agents, the number of nanomedicines in clinical use has hitherto …
Analysis of nanomaterial biocoronas in biological and environmental surroundings
P Zhang, M Cao, AJ Chetwynd, K Faserl… - Nature …, 2024 - nature.com
A biomolecular coating, or biocorona, forms on the surface of engineered nanomaterials
(ENMs) immediately as they enter biological or environmental systems, defining their …
(ENMs) immediately as they enter biological or environmental systems, defining their …
The landscape of gold nanocrystal surface chemistry
KM Greskovich, KM Powderly… - Accounts of chemical …, 2023 - ACS Publications
Conspectus Gold nanoparticles (AuNPs) exhibit unique size-and shape-dependent
properties not obtainable at the macroscale. Gold nanorods (AuNRs), with their morphology …
properties not obtainable at the macroscale. Gold nanorods (AuNRs), with their morphology …
Biofluid specific protein coronas affect lipid nanoparticle behavior in vitro
D van Straten, H Sork, L van de Schepop… - Journal of Controlled …, 2024 - Elsevier
Lipid nanoparticles (LNPs) have successfully entered the clinic for the delivery of mRNA-and
siRNA-based therapeutics, most recently as vaccines for COVID-19. Nevertheless, there is a …
siRNA-based therapeutics, most recently as vaccines for COVID-19. Nevertheless, there is a …
Concentration and composition of the protein corona as a function of incubation time and serum concentration: an automated approach to the protein corona
KM Poulsen, CK Payne - Analytical and Bioanalytical Chemistry, 2022 - Springer
Nanoparticles in contact with proteins form a “corona” of proteins adsorbed on the
nanoparticle surface. Subsequent biological responses are then mediated by the adsorbed …
nanoparticle surface. Subsequent biological responses are then mediated by the adsorbed …
In situ characterization techniques of protein corona around nanomaterials
Nanoparticles (NPs) inevitably interact with proteins upon exposure to biological fluids,
leading to the formation of an adsorption layer known as the “protein corona”. This corona …
leading to the formation of an adsorption layer known as the “protein corona”. This corona …
Biomolecular Corona of Gold Nanoparticles: The Urgent Need for Strong Roots to Grow Strong Branches
Gold nanoparticles (GNPs) are largely employed in diagnostics/biosensors and are among
the most investigated nanomaterials in biology/medicine. However, few GNPbased …
the most investigated nanomaterials in biology/medicine. However, few GNPbased …
Gold-iron oxide (Au/Fe3O4) magnetic nanoparticles as the nanoplatform for binding of bioactive molecules through self-assembly
Nanomedicine plays a crucial role in the development of next-generation therapies. The use
of nanoparticles as drug delivery platforms has become a major area of research in …
of nanoparticles as drug delivery platforms has become a major area of research in …
Adsorption and Molecular Display of a Redox-Active Protein on Gold Nanoparticle Surfaces
KNL Hoang, CJ Murphy - Langmuir, 2023 - ACS Publications
Engineered gold nanoparticles (AuNPs) have great potential in many applications due to
their tunable optical properties, facile synthesis, and surface functionalization via thiol …
their tunable optical properties, facile synthesis, and surface functionalization via thiol …
[HTML][HTML] Unveiling the challenges of engineered protein corona from the proteins' perspective
C Marques, G Borchard, O Jordan - International Journal of Pharmaceutics, 2024 - Elsevier
It is well known that protein corona affects the “biological identity” of nanoparticles (NPs),
which has been seen as both a challenge and an opportunity. Approaches have moved from …
which has been seen as both a challenge and an opportunity. Approaches have moved from …