Acute respiratory distress syndrome in adults: diagnosis, outcomes, long-term sequelae, and management

EA Gorman, CM O'Kane, DF McAuley - The Lancet, 2022 - thelancet.com
Acute respiratory distress syndrome (ARDS) is characterised by acute hypoxaemic
respiratory failure with bilateral infiltrates on chest imaging, which is not fully explained by …

Non-invasive ventilatory support and high-flow nasal oxygen as first-line treatment of acute hypoxemic respiratory failure and ARDS

DL Grieco, SM Maggiore, O Roca, E Spinelli… - Intensive care …, 2021 - Springer
The role of non-invasive respiratory support (high-flow nasal oxygen and noninvasive
ventilation) in the management of acute hypoxemic respiratory failure and acute respiratory …

A new global definition of acute respiratory distress syndrome

MA Matthay, Y Arabi, AC Arroliga… - American journal of …, 2024 - atsjournals.org
Background: Since publication of the 2012 Berlin definition of acute respiratory distress
syndrome (ARDS), several developments have supported the need for an expansion of the …

The Berlin definition of acute respiratory distress syndrome: should patients receiving high-flow nasal oxygen be included?

MA Matthay, BT Thompson, LB Ware - The Lancet Respiratory …, 2021 - thelancet.com
The 2012 Berlin definition of acute respiratory distress syndrome (ARDS) provided validated
support for three levels of initial arterial hypoxaemia that correlated with mortality in patients …

Monitoring lung injury severity and ventilation intensity during mechanical ventilation

E Rezoagli, JG Laffey, G Bellani - Seminars in Respiratory and …, 2022 - thieme-connect.com
Acute respiratory distress syndrome (ARDS) is a severe form of respiratory failure burden by
high hospital mortality. No specific pharmacologic treatment is currently available and its …

The PANDORA study: prevalence and outcome of acute hypoxemic respiratory failure in the Pre-COVID-19 Era

J Villar, JM Mora-Ordoñez, JA Soler… - Critical Care …, 2022 - journals.lww.com
OBJECTIVES: To establish the epidemiological characteristics, ventilator management, and
outcomes in patients with acute hypoxemic respiratory failure (AHRF), with or without acute …

Estimating the attributable fraction of mortality from acute respiratory distress syndrome to inform enrichment in future randomised clinical trials

R Saha, T Pham, P Sinha, MV Maddali, G Bellani… - thorax, 2023 - thorax.bmj.com
Background Efficiency of randomised clinical trials of acute respiratory distress syndrome
(ARDS) depends on the fraction of deaths attributable to ARDS (AFARDS) to which …

Identification of persistent and resolving subphenotypes of acute hypoxemic respiratory failure in two independent cohorts

NA Sathe, LR Zelnick, C Mikacenic, ED Morrell… - Critical Care, 2021 - Springer
Background Acute hypoxemic respiratory failure (HRF) is associated with high morbidity and
mortality, but its heterogeneity challenges the identification of effective therapies. Defining …

What does acute respiratory distress syndrome mean during the COVID-19 pandemic?

SM Brown, ID Peltan, C Barkauskas… - Annals of the …, 2021 - atsjournals.org
Acute Respiratory Distress Syndrome (ARDS) was first described in 1967 as a syndrome of
severe hypoxemia and diffuse bilateral opacities (1). From the beginning, diagnosis of this …

Invasive mechanical ventilation

IMJ Wong, ND Ferguson, M Urner - Intensive care medicine, 2023 - Springer
Mechanical ventilation is provided to up to 20 million patients annually in intensive care
units (ICUs) worldwide. Despite lung-protective mechanical ventilation strategies, the …