Venous thromboembolism: review of clinical challenges, biology, assessment, treatment, and modeling

C Watson, H Saaid, V Vedula, JC Cardenas… - Annals of Biomedical …, 2024 - Springer
Venous thromboembolism (VTE) is a massive clinical challenge, annually affecting millions
of patients globally. VTE is a particularly consequential pathology, as incidence is correlated …

Flexible filaments buckle into helicoidal shapes in strong compressional flows

B Chakrabarti, Y Liu, J LaGrone, R Cortez, L Fauci… - Nature Physics, 2020 - nature.com
The occurrence of coiled or helical morphologies is common in nature, from plant roots to
DNA packaging into viral capsids, as well as in applications such as oil drilling processes. In …

[HTML][HTML] Red blood cell stiffness and adhesion are species-specific properties strongly affected by temperature and medium changes in single cell force spectroscopy

D Baier, T Müller, T Mohr, U Windberger - Molecules, 2021 - mdpi.com
Besides human red blood cells (RBC), a standard model used in AFM-single cell force
spectroscopy (SCFS), little is known about apparent Young's modulus (Ea) or adhesion of …

Viscoelastic flow-induced oscillations of a cantilevered beam in the crossflow of a wormlike micelle solution

AA Dey, Y Modarres-Sadeghi, JP Rothstein - Journal of Non-Newtonian …, 2020 - Elsevier
We investigate the interactions between a cantilevered flexible beam and cross-flow of a
viscoelastic fluid. Unlike Newtonian fluids, viscoelastic fluids exhibit elastic flow instabilities …

The role of plasma in the yield stress of blood

U Windberger, A Sparer… - Clinical Hemorheology …, 2023 - content.iospress.com
BACKGROUND: Yielding and shear elasticity of blood are merely discussed within the
context of hematocrit and erythrocyte aggregation. However, plasma might play a substantial …

[HTML][HTML] Near-Newtonian blood behavior–is it good to be a camel?

U Windberger, R Auer, M Seltenhammer… - Frontiers in …, 2019 - frontiersin.org
From a certain level of exercise-intensity onward, hematocrit increases in horses, which
brings more oxygen carriers into the bloodstream. Camels, however, when used in …

Oscillations of a cantilevered micro beam driven by a viscoelastic flow instability

AA Dey, Y Modarres-Sadeghi, A Lindner, JP Rothstein - Soft Matter, 2020 - pubs.rsc.org
The interaction of flexible structures with viscoelastic flows can result in very rich dynamics.
In this paper, we present the results of the interactions between the flow of a viscoelastic …

Blood flow mechanics

M Fenech, L Haya - Cardiovascular Mechanics, 2018 - api.taylorfrancis.com
Human blood is mostly composed of cells. Typically, red blood cells (RBCs, or erythrocytes)
occupy 40%–45% of the blood volume, whereas the white blood cells (WBCs, or leukocytes) …

Human blood plasma in capillary-size flow: Revealing hidden elasticity and scale dependence

U Windberger, L Noirez - 2020 - hal.science
The dynamical mechanical analysis of blood generally uses models inspired by
conventional flows, assuming scale-independent homogeneous flows and without …

Blood as a suspension of deformable particles

MD Graham - Dynamics of blood cell suspensions in …, 2019 - api.taylorfrancis.com
Red blood cells are very soft and are thus easily deformed as they flow. This deforma-bility is
of course essential for passing through capillary beds, but also plays a role in larger blood …