Neural mechanisms mediating sex differences in motivation for reward: cognitive bias, food, gambling, and drugs of abuse

CA Orsini, TE Brown, TE Hodges… - Journal of …, 2022 - Soc Neuroscience
Sex differences in motivation for food rewards, gambling, and drugs of abuse are modulated
by multiple factors, including sensory stimuli, gonadal hormones, and cognitive bias. Cues …

Cognitive mechanisms underlying decision making involving risk of explicit punishment in male and female rats

LM Truckenbrod, EM Cooper, CA Orsini - Cognitive, Affective, & Behavioral …, 2023 - Springer
Individuals engage in the process of risk-based decision making on a daily basis to navigate
various aspects of life. There are, however, individual differences in this form of decision …

Sex mechanisms as nonbinary influences on cognitive diversity

NM Grissom, N Glewwe, C Chen, E Giglio - Hormones and Behavior, 2024 - Elsevier
Essentially all neuropsychiatric diagnoses show some degree of sex and/or gender
differences in their etiology, diagnosis, or prognosis. As a result, the roles of sex-related …

Dopaminergic modulation of sensitivity to immediate and delayed punishment during decision-making

GL Minnes, AJ Wiener, AE Liley, NW Simon - Cognitive, Affective, & …, 2024 - Springer
Effective decision-making involves careful consideration of all rewarding and aversive
outcomes. Importantly, negative outcomes often occur later in time, leading to …

Dissociable contributions of basolateral amygdala and ventrolateral orbitofrontal cortex to flexible learning under uncertainty

CG Aguirre, JH Woo, JL Romero-Sosa… - Journal of …, 2024 - Soc Neuroscience
Reversal learning measures the ability to form flexible associations between choice
outcomes with stimuli and actions that precede them. This type of learning is thought to rely …

Sex and timing of gonadectomy relative to puberty interact to influence weight, body composition, and feeding behaviors in mice

CM Klappenbach, Q Wang, AL Jensen… - Hormones and …, 2023 - Elsevier
Gonadal sex steroids are important regulators of energy balance in adult rodents, and
gonadectomy (GDX) has opposing effects on weight gain in sexually mature males and …

[HTML][HTML] Understanding sex differences and the translational value of models of persistent substance use despite negative consequences

XJ Maddern, LC Walker, RG Anversa… - … of Learning and …, 2024 - Elsevier
Persistent substance use despite negative consequences is a key facet of substance use
disorder. The last decade has seen the preclinical field adopt the use of punishment to …

Maternal cannabis use alters excitatory inputs to corticostriatal efferent neurons in rat offspring

DE Ginder, HV Weimar, JEM Lindberg, ZDG Fisher… - bioRxiv, 2024 - biorxiv.org
With the recent surge in cannabis legalization across North America, there is legitimate
concern that rates of cannabis use during pregnancy will dramatically increase in the …

To minimize loss or maximize gain? That depends on sleep and gender

SH Mitchell, SA Shea - Sleep, 2022 - academic.oup.com
In a recent issue of SLEEP, Lim et al.[1] report how different forms of sleep loss moderate
risky decision-making, and how this effect is dependent on gender. This was a …

Towards a better understanding of the bidirectional relationship between decision-making and addiction vulnerability

KM Hrelja - 2024 - open.library.ubc.ca
Impaired decision-making is recognized as a diagnostic criterion for many different
psychiatric disorders including gambling disorder and substance use disorders. Habit …