Sphingolipid-mediated regulation in cancer development and treatment is largely ceramide-
centered with the complex sphingolipid metabolic pathways unfolding as attractive targets …

The effects of fumonisins on sphingolipids in turkeys are unknown, except for the increased
sphinganine to sphingosine ratio (Sa: So) used as a biomarker. Fumonisins fed at 20.2 …

Dysregulation of sphingolipid metabolism plays a complex role in hematological
malignancies, beginning with the first historical link between sphingolipids and apoptosis …

Dihydroceramide desaturase (Degs1) catalyses the introduction of a 4, 5-trans double bond
into dihydroceramide to form ceramide. We show here that Degs1 is polyubiquitinated in …

Simple Summary Cancer is an incredibly smart disease, so much so that it can entirely
reprogram our cells' metabolism to ensure its survival and dissemination. Lymphomas are a …