The aging gut microbiome and its impact on host immunity
The microbiome plays a fundamental role in the maturation, function, and regulation of the
host-immune system from birth to old age. In return, the immune system has co-evolved a …
host-immune system from birth to old age. In return, the immune system has co-evolved a …
The degree of frailty as a translational measure of health in aging
Frailty is a multiply determined, age-related state of increased risk for adverse health
outcomes. We review how the degree of frailty conditions the development of late-life …
outcomes. We review how the degree of frailty conditions the development of late-life …
Risk factors associated with all-cause 30-day mortality in nursing home residents with COVID-19
Importance The coronavirus disease 2019 (COVID-19) pandemic has severely affected
nursing homes. Vulnerable nursing home residents are at high risk for adverse outcomes …
nursing homes. Vulnerable nursing home residents are at high risk for adverse outcomes …
Association of Toll-like receptor 7 variants with life-threatening COVID-19 disease in males: findings from a nested case-control study
Background: Recently, loss-of-function variants in TLR7 were identified in two families in
which COVID-19 segregates like an X-linked recessive disorder environmentally …
which COVID-19 segregates like an X-linked recessive disorder environmentally …
Clinical characteristics and risk factors for mortality in very old patients hospitalized with COVID-19 in Spain
JM Ramos-Rincon, V Buonaiuto, M Ricci… - The Journals of …, 2021 - academic.oup.com
Background Advanced age is a well-known risk factor for poor prognosis in COVID-19.
However, few studies have specifically focused on very old inpatients with COVID-19. This …
However, few studies have specifically focused on very old inpatients with COVID-19. This …
How Sweden approached the COVID‐19 pandemic: Summary and commentary on the National Commission Inquiry
JF Ludvigsson - Acta Paediatrica, 2023 - Wiley Online Library
Aim Sweden initially chose a different disease prevention and control path during the
pandemic than many other European countries. In June 2020, the Swedish Government …
pandemic than many other European countries. In June 2020, the Swedish Government …
Frailty as a predictor of mortality among patients with COVID-19: a systematic review and meta-analysis
XM Zhang, J Jiao, J Cao, XP Huo, C Zhu, XJ Wu… - BMC geriatrics, 2021 - Springer
Background A large number of studies have explored the association between frailty and
mortality among COVID-19 patients, with inconsistent results. The aim of this meta-analysis …
mortality among COVID-19 patients, with inconsistent results. The aim of this meta-analysis …
Excess mortality from COVID-19: weekly excess death rates by age and sex for Sweden and its most affected region
Background Sweden has one of the highest numbers of COVID-19 deaths per inhabitant
globally. However, absolute death counts can be misleading. Estimating age-and sex …
globally. However, absolute death counts can be misleading. Estimating age-and sex …
Prevalence and predictors of persistence of COVID-19 symptoms in older adults: a single-center study
Objectives Symptom persistence weeks after laboratory-confirmed severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) clearance is a relatively common long-term …
syndrome coronavirus 2 (SARS-CoV-2) clearance is a relatively common long-term …
Association of frailty with outcomes in individuals with COVID‐19: a living review and meta‐analysis
F Dumitrascu, KE Branje, ES Hladkowicz… - Journal of the …, 2021 - Wiley Online Library
Abstract Background and Objectives Frailty leaves older adults vulnerable to adverse health
outcomes. Frailty assessment is recommended by multiple COVID‐19 guidelines to inform …
outcomes. Frailty assessment is recommended by multiple COVID‐19 guidelines to inform …