Species in the genus Pseudomonas thrive in a diverse set of ecological niches and include
crucial pathogens, such as the human pathogen Pseudomonas aeruginosa and the plant …

Salmonella Typhimurium has a broad arsenal of genes that are tightly regulated and
coordinated to facilitate adaptation to the various host environments it colonizes. The …

Bacterial H-NS forms nucleoprotein filaments that spread on DNA and bridge distant DNA
sites. H-NS filaments co-localize with sites of Rho-dependent termination in Escherichia coli …

Background We previously isolated a Klebsiella pneumoniae strain, NTUH-K2044, from a
community-acquired pyogenic liver abscess (PLA) patient. Analysis of the NTUH-K2044 …

In Escherichia coli and Salmonella, many genes silenced by the nucleoid structuring protein
H-NS are activated upon inhibiting Rho-dependent transcription termination. This response …

In all living cells, genomic DNA is compacted through interactions with dedicated proteins
and/or the formation of plectonemic coils. In bacteria, DNA compaction is achieved …

The H-NS (heat-stable nucleoid structuring) protein affects both nucleoid compaction and
global gene regulation. H-NS appears to act primarily as a silencer of AT-rich genetic …

Silent genes are DNA sequences that are generally not expressed or expressed at a very
low level. These genes become active as a result of mutation, recombination, or insertion …

Shigella spp. are one of the leading causes of infectious diarrheal diseases. They are
Escherichia coli pathovars that are characterized by the harboring of a large plasmid that …

As an environment-dependent pleiotropic gene regulator in Gram-negative bacteria, the H-
NS protein is crucial for adaptation and toxicity control of human pathogens such as …