Pseudomonas predators: understanding and exploiting phage–host interactions
J De Smet, H Hendrix, BG Blasdel… - Nature Reviews …, 2017 - nature.com
Species in the genus Pseudomonas thrive in a diverse set of ecological niches and include
crucial pathogens, such as the human pathogen Pseudomonas aeruginosa and the plant …
crucial pathogens, such as the human pathogen Pseudomonas aeruginosa and the plant …
[HTML][HTML] Evolution of Salmonella-Host Cell Interactions through a Dynamic Bacterial Genome
Salmonella Typhimurium has a broad arsenal of genes that are tightly regulated and
coordinated to facilitate adaptation to the various host environments it colonizes. The …
coordinated to facilitate adaptation to the various host environments it colonizes. The …
[HTML][HTML] Bridged filaments of histone-like nucleoid structuring protein pause RNA polymerase and aid termination in bacteria
MV Kotlajich, DR Hron, BA Boudreau, Z Sun… - Elife, 2015 - elifesciences.org
Bacterial H-NS forms nucleoprotein filaments that spread on DNA and bridge distant DNA
sites. H-NS filaments co-localize with sites of Rho-dependent termination in Escherichia coli …
sites. H-NS filaments co-localize with sites of Rho-dependent termination in Escherichia coli …
Klebsiella pneumoniae Type VI Secretion System Contributes to Bacterial Competition, Cell Invasion, Type-1 Fimbriae Expression, and In Vivo Colonization
PF Hsieh, YR Lu, TL Lin, LY Lai… - The Journal of infectious …, 2019 - academic.oup.com
Background We previously isolated a Klebsiella pneumoniae strain, NTUH-K2044, from a
community-acquired pyogenic liver abscess (PLA) patient. Analysis of the NTUH-K2044 …
community-acquired pyogenic liver abscess (PLA) patient. Analysis of the NTUH-K2044 …
Pervasive transcription enhances the accessibility of H-NS–silenced promoters and generates bistability in Salmonella virulence gene expression
N Figueroa-Bossi… - Proceedings of the …, 2022 - National Acad Sciences
In Escherichia coli and Salmonella, many genes silenced by the nucleoid structuring protein
H-NS are activated upon inhibiting Rho-dependent transcription termination. This response …
H-NS are activated upon inhibiting Rho-dependent transcription termination. This response …
[HTML][HTML] Transcription-driven DNA supercoiling counteracts H-NS-mediated gene silencing in bacterial chromatin
N Figueroa-Bossi, R Fernández-Fernández… - Nature …, 2024 - nature.com
In all living cells, genomic DNA is compacted through interactions with dedicated proteins
and/or the formation of plectonemic coils. In bacteria, DNA compaction is achieved …
and/or the formation of plectonemic coils. In bacteria, DNA compaction is achieved …
Xenogeneic silencing and its impact on bacterial genomes
K Singh, JN Milstein, WW Navarre - Annual review of …, 2016 - annualreviews.org
The H-NS (heat-stable nucleoid structuring) protein affects both nucleoid compaction and
global gene regulation. H-NS appears to act primarily as a silencer of AT-rich genetic …
global gene regulation. H-NS appears to act primarily as a silencer of AT-rich genetic …
[HTML][HTML] Silent genes: Antimicrobial resistance and antibiotic production
M Stasiak, E Maćkiw, J Kowalska, K Kucharek… - Polish Journal of …, 2021 - sciendo.com
Silent genes are DNA sequences that are generally not expressed or expressed at a very
low level. These genes become active as a result of mutation, recombination, or insertion …
low level. These genes become active as a result of mutation, recombination, or insertion …
[HTML][HTML] The T3SS of Shigella: Expression, Structure, Function, and Role in Vacuole Escape
W Bajunaid, N Haidar-Ahmad, AH Kottarampatel… - Microorganisms, 2020 - mdpi.com
Shigella spp. are one of the leading causes of infectious diarrheal diseases. They are
Escherichia coli pathovars that are characterized by the harboring of a large plasmid that …
Escherichia coli pathovars that are characterized by the harboring of a large plasmid that …
H-NS uses an autoinhibitory conformational switch for environment-controlled gene silencing
UF Shahul Hameed, C Liao… - Nucleic acids …, 2019 - academic.oup.com
As an environment-dependent pleiotropic gene regulator in Gram-negative bacteria, the H-
NS protein is crucial for adaptation and toxicity control of human pathogens such as …
NS protein is crucial for adaptation and toxicity control of human pathogens such as …