Emerging evidence links the growth hormone (GH)-insulin-like growth factor-1 (IGF1)
endocrine axis to cancer development. While this putative correlation is of major …

Purpose Non-small cell lung cancer (NSCLC) accounts for about 85% in all cases of lung
cancer. In recent years, molecular targeting drugs for NSCLC have been developed rapidly …

Background: Accumulating studies manifest that BTB and CNC homology 1 (BACH1)
facilitates multiple malignancies progression and metastasis, and targeting the BACH1 …

Metastasis is the major reason for the high mortality of colorectal cancer (CRC) patients and
its molecular mechanism remains unclear. Here, we report a novel role of Homeobox A13 …

The identification of a series of attributes or hallmarks that are shared by virtually all cancer
cells constitutes a true milestone in cancer research. The conceptualization of a catalogue of …

Development of high-throughput technologies helped to decipher tumor genomic
landscapes revealing actionable molecular alterations. We aimed to rank the level of …

Stem cells work with their niches harmoniously during development. This concept has been
extended to cancer pathology for cancer stem cells (CSCs) or cancer reprogramming. IGF …

Background Circular RNA (circRNA) is a novel molecular marker and target candidate that is
closely associated with tumor invasion and migration. The mechanism of action of …

In prostate cancer, distant organ metastasis is the leading cause of patient death. Although
the mechanism of malignant tumor metastasis is unclear, studies have confirmed that …

Several studies show that triple-negative breast cancer (TNBC) patients have the lowest
vitamin D concentration among all breast cancer types, suggesting that this vitamin may …