Liposome composition in drug delivery design, synthesis, characterization, and clinical application

DE Large, RG Abdelmessih, EA Fink… - Advanced drug delivery …, 2021 - Elsevier
Liposomal drug delivery represents a highly adaptable therapeutic platform for treating a
wide range of diseases. Natural and synthetic lipids, as well as surfactants, are commonly …

Amino acid metabolism in immune cells: essential regulators of the effector functions, and promising opportunities to enhance cancer immunotherapy

L Yang, Z Chu, M Liu, Q Zou, J Li, Q Liu… - Journal of hematology & …, 2023 - Springer
Amino acids are basic nutrients for immune cells during organ development, tissue
homeostasis, and the immune response. Regarding metabolic reprogramming in the tumor …

Why nanoparticles prefer liver macrophage cell uptake in vivo

W Ngo, S Ahmed, C Blackadar, B Bussin, Q Ji… - Advanced Drug Delivery …, 2022 - Elsevier
Effective delivery of therapeutic and diagnostic nanoparticles is dependent on their ability to
accumulate in diseased tissues. However, most nanoparticles end up in liver macrophages …

Overcoming the blood–brain barrier: the role of nanomaterials in treating neurological diseases

D Furtado, M Björnmalm, S Ayton, AI Bush… - Advanced …, 2018 - Wiley Online Library
Therapies directed toward the central nervous system remain difficult to translate into
improved clinical outcomes. This is largely due to the blood–brain barrier (BBB), arguably …

Progress in tumor-associated macrophage (TAM)-targeted therapeutics

C Ngambenjawong, HH Gustafson, SH Pun - Advanced drug delivery …, 2017 - Elsevier
As an essential innate immune population for maintaining body homeostasis and warding
off foreign pathogens, macrophages display high plasticity and perform diverse supportive …

The CCL20-CCR6 axis in cancer progression

S Kadomoto, K Izumi, A Mizokami - International journal of molecular …, 2020 - mdpi.com
Chemokines, which are basic proteins that exert their effects via G protein-coupled receptors
and a subset of the cytokine family, are mediators deeply involved in leukocyte migration …

Macrophage exosomes as natural nanocarriers for protein delivery to inflamed brain

D Yuan, Y Zhao, WA Banks, KM Bullock, M Haney… - Biomaterials, 2017 - Elsevier
Recent work has stimulated interest in the use of exosomes as nanocarriers for delivery of
small drugs, RNAs, and proteins to the central nervous system (CNS). To overcome the …

Engineered strategies to enhance tumor penetration of drug-loaded nanoparticles

M Souri, M Soltani, FM Kashkooli… - Journal of Controlled …, 2022 - Elsevier
Nanocarriers have been widely employed in preclinical studies and clinical trials for the
delivery of anticancer drugs. The most important causes of failure in clinical translation of …

Human breast milk: from food to active immune response with disease protection in infants and mothers

GAG Lokossou, L Kouakanou, A Schumacher… - Frontiers in …, 2022 - frontiersin.org
Breastfeeding is associated with long-term wellbeing including low risks of infectious
diseases and non-communicable diseases such as asthma, cancer, autoimmune diseases …

Bridging bio–nano science and cancer nanomedicine

M Bjornmalm, KJ Thurecht, M Michael, AM Scott… - ACS …, 2017 - ACS Publications
The interface of bio–nano science and cancer medicine is an area experiencing much
progress but also beset with controversy. Core concepts of the field eg, the enhanced …