Chronic exposure to intermittent hypoxia (CIH) elicits plasticity of the carotid sinus and
phrenic nerves via reactive oxygen species (ROS). To determine whether CIH-induced …

Recent studies have shown that acute intermittent hypoxia (IH) induces sensory plasticity of
the carotid body manifested as sensory long-term facilitation (LTF), which requires prior …

Sleep apnea is a prevalent respiratory disease in which episodic cessation of breathing
causes intermittent hypoxia. Patients with sleep apnea and rodents exposed to intermittent …

Carotid bodies and neonatal adrenal medullary chromaffin cells (AMC) respond rapidly to
acute hypoxia before compromising cellular functions. Responses to acute hypoxia are …

Autonomic dysfunction is involved in the development of hypertension in humans with
obstructive sleep apnea, and animals exposed to chronic intermittent hypoxia (CIH). It has …

New findings• What is the central question of this study? What mechanisms mediate chronic
intermittent hypoxia‐induced increases in endothelin‐1 in the carotid body?• What is the …

Abstract Purpose of Review Obstructive sleep apnea (OSA), featured by chronic intermittent
hypoxia (CIH), is an independent risk for systemic hypertension (HTN) and is associated …

We examined whether exposure to intermittent hypoxia (IH) during wakefulness impacted on
the apnea/hypopnea index (AHI) during sleep in individuals with sleep apnea. Participants …

Exposure to cyclic intermittent hypoxia (CIH) is associated with elevated arterial pressure
and sustained sympathoexcitation, but the causes of the augmented sympathetic activity …

Arterial chemoreceptors in the carotid body are central to the chemical control of breathing in
the chemotransduction of physiological stimuli in the arterial blood for eliciting the …