Synthesis and biological evaluation of new kojic acid-1, 3, 4-oxadiazole hybrids as tyrosinase inhibitors and their application in the anti-browning of fresh-cut …

G Wang, M He, Y Huang, Z Peng - Food Chemistry, 2023 - Elsevier
In the food industry, inhibition of tyrosinase activity is considered as one of the main means
to prevent browning. Therefore, fourteen kojic acid-1, 3, 4-oxadiazole hybrids (5a–5n) were …

Preparation and structure-activity relationship of highly active black garlic polysaccharides

J Liang, Y Zhao, F Yang, L Zheng, Y Ma, Q Liu… - International Journal of …, 2022 - Elsevier
The aim of this study was to establish a method to improve the biological activity of
polysaccharides. Three acid-treated polysaccharides (BGPS-2, BGPS-3 and BGPS-4) were …

Inhibition mechanisms of four ellagitannins from terminalia chebula fruits on acetylcholinesterase by inhibition kinetics, spectroscopy and molecular docking analyses

YJ Li, CC Liang, L Jin, J Chen - Spectrochimica Acta Part A: Molecular and …, 2023 - Elsevier
Acetylcholinesterase (AChE) is an important therapeutic target for the treatment of
Alzheimer's disease (AD), and the development of natural AChE inhibitors as candidates …

New insights into the inhibition of hesperetin on polyphenol oxidase: inhibitory kinetics, binding characteristics, conformational change and computational simulation

X Hong, X Luo, L Wang, D Gong, G Zhang - Foods, 2023 - mdpi.com
The inhibitory activity of hesperetin on polyphenol oxidase (PPO) and their interaction
characteristics were investigated using multiple spectroscopic methods and computational …

Investigation on the inhibition mechanism and binding behavior of paeonol to tyrosinase and its anti-browning property by multi-spectroscopic and molecular docking …

X Min, L Lu, X Xu, Y Wen, X Zheng - International Journal of Biological …, 2023 - Elsevier
Paeonol, as one effective tyrosinase inhibitor, had been used as food preservative and
clinical medication for skin disorders. In this study, the inhibition mechanism and binding …

In vitro determination of the skin anti-aging potential of four-component plant-based ingredient

J Quiles, M Cabrera, J Jones, M Tsapekos, N Caturla - Molecules, 2022 - mdpi.com
The beauty industry is actively searching for solutions to prevent skin aging. Some of the
crucial elements protecting cells from the aging process are telomere shortening …

Silver Carp (Hypophthalmichthys molitrix) Scale Collagen Peptides-1 (SCPs1) Inhibit Melanogenesis through Downregulation of the cAMP-CREB Signaling Pathway

HL Li, MJ Li, GQ Xiong, J Cai, T Liao, XY Zu - Nutrients, 2023 - mdpi.com
The mechanism of silver carp scale collagen peptides (SCPs1) on melanogenesis and its
mechanism of action were examined in mouse melanoma cells (B16). The cell viability and …

A comprehensive study to explore tyrosinase inhibitory medicinal plants and respective phytochemicals for hyperpigmentation; molecular approach and future …

A Insaf, R Parveen, G Gautam, M Samal… - Current …, 2023 - ingentaconnect.com
Tyrosinase is a copper-containing key substance in the pigmentation of mammalian hair and
skin. Melanin synthesis is influenced by a variety of extrinsic and internal variables …

Skin anti-aging efficacy of a four-botanical blend dietary ingredient: A randomized, double blind, clinical study

V Nobile, I Schiano, L Germani, E Cestone, P Navarro… - Cosmetics, 2023 - mdpi.com
Plant polyphenols have been found to be effective in preventing or reducing different skin
alterations. A dietary approach based on these compounds could be a safe and effective …

Rational Design, Synthesis, in Vitro, and in Silico Studies of Chlorophenylquinazolin‐4(3H)‐One Containing Different Aryl Acetohydrazides as Tyrosinase Inhibitors

M Hajimiri, M Khosravikia… - Chemistry & …, 2022 - Wiley Online Library
Tyrosinase plays a pivotal role in the hyperpigmentation and enzymatic browning of fruit and
vegetable. Therefore, tyrosinase inhibitors can be of interest in industries as depigmentation …