Redox signaling at the crossroads of human health and disease

J Zuo, Z Zhang, M Luo, L Zhou, EC Nice, W Zhang… - MedComm, 2022 - Wiley Online Library
Redox biology is at the core of life sciences, accompanied by the close correlation of redox
processes with biological activities. Redox homeostasis is a prerequisite for human health …

[HTML][HTML] Premature ovarian insufficiency: a review on the role of oxidative stress and the application of antioxidants

YQ Shi, XT Zhu, SN Zhang, YF Ma, YH Han… - Frontiers in …, 2023 - frontiersin.org
Normal levels of reactive oxygen species (ROS) play an important role in regulating follicular
growth, angiogenesis and sex hormone synthesis in ovarian tissue. When the balance …

The process of ovarian aging: it is not just about oocytes and granulosa cells

A Camaioni, MA Ucci, L Campagnolo… - Journal of assisted …, 2022 - Springer
Ovarian age is classically considered the main cause of female reproductive infertility. In
women, the process proceeds as an ongoing decline in the primordial follicle stockpile and it …

[HTML][HTML] Advances in oocyte maturation in vivo and in vitro in mammals

Y Jiang, Y He, X Pan, P Wang, X Yuan… - International journal of …, 2023 - mdpi.com
The quality and maturation of an oocyte not only play decisive roles in fertilization and
embryo success, but also have long-term impacts on the later growth and development of …

Mechanisms of action of non-enzymatic antioxidants to control oxidative stress during in vitro follicle growth, oocyte maturation, and embryo development

BR Silva, JRV Silva - Animal reproduction science, 2023 - Elsevier
In vitro follicle growth and oocyte maturation still has a series of limitations, since not all
oocytes matured in vitro have the potential to develop in viable embryos. One of the factors …

[HTML][HTML] Mitofusins: from mitochondria to fertility

S Zhao, N Heng, H Wang, H Wang, H Zhang… - Cellular and Molecular …, 2022 - Springer
Germ cell formation and embryonic development require ATP synthesized by mitochondria.
The dynamic system of the mitochondria, and in particular, the fusion of mitochondria, are …

[HTML][HTML] Intercellular communication in the cumulus–oocyte complex during folliculogenesis: A review

J Xie, X Xu, S Liu - Frontiers in Cell and Developmental Biology, 2023 - frontiersin.org
During folliculogenesis, the oocyte and surrounding cumulus cells form an ensemble called
the cumulus-oocyte complex (COC). Due to their interdependence, research on the COC …

Endoplasmic reticulum stress exacerbates microplastics-induced toxicity in animal cells

Z Wang, S Liu, Z Cheng, G Xu, F Li, Q Bu… - Food Research …, 2024 - Elsevier
Human and animal exposure to microplastics (MPs) contained in food is inevitable because
of their widespread existence in the environment. Nevertheless, MPs toxicity studies in …

Intermittent fasting reverses the declining quality of aged oocytes

C Li, H Zhang, H Wu, R Li, D Wen, Y Tang… - Free Radical Biology …, 2023 - Elsevier
Decreased oocyte quality and compromised embryo development are particularly prevalent
in older females, but the aging-related cellular processes and effective ameliorative …

[HTML][HTML] Melatonin improves the quality of rotenone-exposed mouse oocytes through association with histone modifications

X Wang, H Li, H Mu, S Zhang, Y Li, X Han… - Ecotoxicology and …, 2023 - Elsevier
Rotenone, an insecticide that inhibits mitochondrial complex I and generates oxidative
stress, is responsible for neurological disorders and affects the female reproductive system …