The voltage-dependent anion channel 1 (VDAC1) protein, is an important regulator of
mitochondrial function, and serves as a mitochondrial gatekeeper, with responsibility for …

Cadmium (Cd) is one of the most toxic metals without biological function, and its
accumulation in living organisms has been reported. The kidney is a target organ in Cd …

Oxidative stress results from the disruption of the redox system marked by a notable
overproduction of reactive oxygen species. There are four major sources of reactive oxygen …

Classically, mitochondria have largely been believed to influence the development of illness
by modulating cell metabolism and determining the rate of production of high-energy …

The underlying therapeutic mechanism of renal tubular epithelium repair of diabetic
nephropathy (DN) by bone marrow-derived mesenchymal stem cells (BM-MSCs) has not …

The NOD-like receptor family, pyrin domain containing-3 (NLRP3) inflammasome has been
implicated in renal inflammation and fibrosis. However, the biological function of …

Acute kidney injury and chronic kidney disease are among the most common non-
communicable diseases in the developed world, with increasing prevalence. Patients with …

Staphylococcus aureus bacteremia (SaB) causes significant disease in humans, carrying
mortality rates of∼ 25%. The ability to rapidly predict SaB patient responses and guide …

The high-throughput, high-resolution phenotyping enabled by metabolomics has been
applied increasingly to a variety of questions in nephrology research. This article provides …

Mesenchymal stromal cells (MSCs) are renoprotective and drive regeneration following
injury, although cellular targets of such an effect are still ill-defined. Here, we show that …