Role of overweight and obesity in gastrointestinal disease
S Emerenziani, M Pier Luca Guarino, LM Trillo Asensio… - Nutrients, 2019 - mdpi.com
The prevalence of obesity is increasing worldwide, leading to a severe impairment of overall
health. Actually, obesity has been associated with several pathological conditions, causing …
health. Actually, obesity has been associated with several pathological conditions, causing …
Insights into the multifactorial causation of obesity by integrated genetic and epigenetic analysis
S Diels, W Vanden Berghe, W Van Hul - Obesity Reviews, 2020 - Wiley Online Library
Obesity is a highly heritable multifactorial disease that places an enormous burden on
human health. Its increasing prevalence and the concomitant‐reduced life expectancy has …
human health. Its increasing prevalence and the concomitant‐reduced life expectancy has …
Altered adipose tissue DNA methylation status in metabolic syndrome: relationships between global DNA methylation and specific methylation at adipogenic, lipid …
D Castellano-Castillo, I Moreno-Indias… - Journal of clinical …, 2019 - mdpi.com
Metabolic syndrome (MetS) has been postulated to increase the risk for type 2 diabetes,
cardiovascular disease and cancer. Adipose tissue (AT) plays an important role in metabolic …
cardiovascular disease and cancer. Adipose tissue (AT) plays an important role in metabolic …
Impact of aerobic exercise and fatty acid supplementation on global and gene-specific DNA methylation
Lifestyle interventions, including exercise and dietary supplementation, can modify DNA
methylation and exert health benefits; however, the underlying mechanisms are poorly …
methylation and exert health benefits; however, the underlying mechanisms are poorly …
Impacts of eccentric resistance exercise on DNA methylation of candidate genes for inflammatory cytokines in skeletal muscle and leukocytes of healthy males
Physical inactivity and a poor diet increase systemic inflammation, while chronic
inflammation can be reduced through exercise and nutritional interventions. The …
inflammation can be reduced through exercise and nutritional interventions. The …
Adipose cell-free DNA in diabetes
FM Humardani, LT Mulyanata, SED Putra - Clinica Chimica Acta, 2023 - Elsevier
Cancer-associated necrosis is a well-known source of cell-free DNA (cfDNA). However, the
origins of cfDNA are not strictly limited to cancer. Additionally, dietary exposure induces …
origins of cfDNA are not strictly limited to cancer. Additionally, dietary exposure induces …
Interleukin‐13 and its signaling pathway is associated with obesity‐related colorectal tumorigenesis
S Matsui, K Okabayashi, M Tsuruta, K Shigeta… - Cancer …, 2019 - Wiley Online Library
The incidence of colorectal cancer (CRC) has been on the rise, which is linked to the
increasing prevalence of obesity, based on global epidemiological evidence. Although …
increasing prevalence of obesity, based on global epidemiological evidence. Although …
Adipose tissue epigenetic profile in obesity-related dysglycemia-a systematic review
S Andrade, T Morais, I Sandovici, AL Seabra… - Frontiers in …, 2021 - frontiersin.org
Background Obesity is a major risk factor for dysglycemic disorders, including type 2
diabetes (T2D). However, there is wide phenotypic variation in metabolic profiles. Tissue …
diabetes (T2D). However, there is wide phenotypic variation in metabolic profiles. Tissue …
Correlation analysis of microribonucleic acid‐155 and microribonucleic acid‐29 with type 2 diabetes mellitus, and the prediction and verification of target genes
J Zhu, C Wang, X Zhang, T Qiu, Y Ma… - Journal of Diabetes …, 2021 - Wiley Online Library
Abstract Aims/Introduction Microribonucleic acid‐155 (microRNA155) and microRNA29 are
reported to inhibit glucose metabolism in some cell and animal models, but no evidence …
reported to inhibit glucose metabolism in some cell and animal models, but no evidence …
Proteomic analysis of serum lysine acetylation in Uyghur patients with T2DM
L Yin, G Feng, C Huang, W Cai - Frontiers in Molecular Biosciences, 2022 - frontiersin.org
Lysine acetylation is a reversible modification process after protein translation, which plays a
key regulatory role in various metabolic diseases such as diabetes. The prevalence of type 2 …
key regulatory role in various metabolic diseases such as diabetes. The prevalence of type 2 …