Human ESC-derived vascular cells promote vascular regeneration in a HIF-1α dependent manner

J Lei, X Jiang, D Huang, Y Jing, S Yang, L Geng… - Protein & …, 2024 - academic.oup.com
Abstract Hypoxia-inducible factor (HIF-1α), a core transcription factor responding to changes
in cellular oxygen levels, is closely associated with a wide range of physiological and …

The role of Klotho and FGF23 in cardiovascular outcomes of diabetic patients with chronic limb threatening ischemia: a prospective study

F Biscetti, MM Rando, AL Cecchini, MA Nicolazzi… - Scientific Reports, 2023 - nature.com
Cardiovascular complications after lower extremity revascularization (LER) are common in
diabetic patients with peripheral arterial disease (PAD) and chronic limb threatening …

Intercellular adhesion molecule 1: more than a leukocyte adhesion molecule

CD Haydinger, LM Ashander, ACR Tan, JR Smith - Biology, 2023 - mdpi.com
Simple Summary Intercellular adhesion molecule 1 (ICAM-1) is a protein produced by cells
in blood vessel walls, as well as many other cell types. It localizes to the surface of these …

Clinical potential of hydrogen sulfide in peripheral arterial disease

C Bechelli, D Macabrey, S Deglise… - International Journal of …, 2023 - mdpi.com
Peripheral artery disease (PAD) affects more than 230 million people worldwide. PAD
patients suffer from reduced quality of life and are at increased risk of vascular complications …

Factors associated with non-adherence to angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in older patients with peripheral arterial …

M Wawruch, M Petrova, T Tesar, J Murin… - Frontiers in …, 2023 - frontiersin.org
Introduction: As in other chronic conditions, medication adherence is important in the
treatment of peripheral arterial disease (PAD). Our study aimed at a) analysing non …

Molecular mechanisms of obesity-induced development of insulin resistance and promotion of amyloid-β accumulation: Dietary therapy using weak organic acids via …

Y Marunaka - Biomolecules, 2023 - mdpi.com
Insulin resistance is one of the etiologies of type 2 diabetes mellitus (T2DM) and has been
suggested to contribute to the development of Alzheimer's disease by promoting amyloid-β …

Effect of brief counseling by allied health professionals on step count of people with peripheral artery disease: A randomized clinical trial

J Golledge, L Yip, A Venn, AS Leicht… - JAMA …, 2023 - jamanetwork.com
Importance It is unclear how to effectively promote walking in people with peripheral artery
disease (PAD). Objective To test whether brief counseling delivered by allied health …

Nuclear receptors as potential therapeutic targets in peripheral arterial disease and related myopathy

A Kumar, VA Narkar - The FEBS Journal, 2023 - Wiley Online Library
Peripheral arterial disease (PAD) is a prevalent cardiovascular complication of limb vascular
insufficiency, causing ischemic injury, mitochondrial metabolic damage and functional …

Current management of peripheral artery disease: focus on pharmacotherapy

J Golledge, ME Fernando, DG Armstrong - Drugs, 2022 - Springer
Peripheral artery disease (PAD) is the occlusion or narrowing of the arteries supplying the
lower extremities. Peripheral artery disease has been estimated to affect approximately 240 …

[HTML][HTML] Peripheral vascular remodeling during ischemia

S Lin, R Lin, H Zhang, Q Xu, Y He - Frontiers in Pharmacology, 2022 - frontiersin.org
About 230 million people worldwide suffer from peripheral arterial disease (PAD), and the
prevalence is increasing year by year. Multiple risk factors, including smoking, dyslipidemia …