Background and Purpose—Large artery intracranial occlusive disease (LAICOD) is a
common and important stroke subtype. In this commentary, we review key epidemiological …

Worldwide, stroke is a leading cause of death and disability. Recombinant tissue
plasminogen activator (rtPA) was approved a decade ago for the treatment of acute ischemic …

Background and Purpose—The authors present an overview of the current evidence and
management recommendations for evaluation and treatment of adults with acute ischemic …

Objective: To review the use of transcranial Doppler ultrasonography (TCD) and transcranial
color-coded sonography (TCCS) for diagnosis. Methods: The authors searched the literature …

The importance of intracranial atherosclerotic disease (ICAD) as a cause of stroke is
underscored as compared to that of extracranial carotid stenosis and nonvalvular atrial …

Background and Purpose—Cilostazol, a phosphodiesterase inhibitor, has been reported to
reduce restenosis rate after coronary angioplasty and stenting. This study was performed to …

Background and Purpose—The goal of this study was to document the long-term outcome of
ischemic stroke patients in a population with predominant intracranial atherosclerosis and …

Objective—To assess the safety and clinical efficacy of stenting for patients with symptomatic
M1 stenosis of middle cerebral artery (MCA), and to assess the significance of classification …

Background and Purpose—An optimal strategy for management of symptomatic intracranial
atherosclerotic stenosis (ICAS) has not yet been established. We compared the efficacy of 2 …

Background and Purpose—Although recent trials have suggested that stenting is worse than
medical therapy for patients with severe symptomatic intracranial atherosclerotic stenosis, it …