SLN and NLC for topical, dermal, and transdermal drug delivery

EB Souto, I Baldim, WP Oliveira, R Rao… - Expert opinion on …, 2020 - Taylor & Francis
Introduction From a biopharmaceutical standpoint, the skin is recognized as an interesting
route for drug delivery. In general, small molecules are able to penetrate the stratum …

Nanoparticles as safe and effective delivery systems of antifungal agents: Achievements and challenges

GM Soliman - International journal of pharmaceutics, 2017 - Elsevier
Invasive fungal infections are becoming a major health concern in several groups of patients
leading to severe morbidity and mortality. Moreover, cutaneous fungal infections are a major …

Engineered nanomaterial uptake and tissue distribution: from cell to organism

H Kettiger, A Schipanski, P Wick… - International journal of …, 2013 - Taylor & Francis
Improved understanding of interactions between nanoparticles and biological systems is
needed to develop safety standards and to design new generations of nanomaterials. This …

Naringenin-loaded solid lipid nanoparticles: preparation, controlled delivery, cellular uptake, and pulmonary pharmacokinetics

P Ji, T Yu, Y Liu, J Jiang, J Xu, Y Zhao… - Drug design …, 2016 - Taylor & Francis
Naringenin (NRG), a flavonoid compound, had been reported to exhibit extensive
pharmacological effects, but its water solubility and oral bioavailability are only~ 46±6 µg/mL …

Comprehensive review on additives of topical dosage forms for drug delivery

T Garg, G Rath, AK Goyal - Drug delivery, 2015 - Taylor & Francis
Skin is the largest organ of the human body and plays the most important role in protecting
against pathogen and foreign matter. Three important modes such as topical, regional and …

Exploiting solid lipid nanoparticles and nanostructured lipid carriers for drug delivery against cutaneous fungal infections

VHS Araujo, L Delello Di Filippo, JL Duarte… - Critical reviews in …, 2021 - Taylor & Francis
Several types of cutaneous fungal infections can affect the population worldwide, such as
dermatophytosis, cutaneous candidiasis, onychomycosis, and sporotrichosis. However, oral …

Superficial Dermatophytosis across the World's Populations: Potential Benefits from Nanocarrier-Based Therapies and Rising Challenges

P Keshwania, N Kaur, J Chauhan, G Sharma… - ACS …, 2023 - ACS Publications
The most prevalent infection in the world is dermatophytosis, which is a major issue with
high recurrence and can affect the entire body including the skin, hair, and nails. The major …

Lipid based nanocarriers: A novel paradigm for topical antifungal therapy

S Nene, S Shah, N Rangaraj, NK Mehra… - Journal of Drug Delivery …, 2021 - Elsevier
Superficial fungal infections manifesting the skin have become prevalent today. Even though
there has been a substantial number of antifungal drugs approved for treating topical fungal …

Luteolin-loaded solid lipid nanoparticles synthesis, characterization, & improvement of bioavailability, pharmacokinetics in vitro and vivo studies

H Dang, MHW Meng, H Zhao, J Iqbal, R Dai… - Journal of Nanoparticle …, 2014 - Springer
Abstract Luteolin (LU, 5, 7, 3′, 4′-tetrahydroxyflavone) most active compound in Chinese
herbal flavones has been acting as a antimicrobial, anti-inflammatory, anti-cancer, and …

[HTML][HTML] Novel anti-psoriatic nanostructured lipid carriers for the cutaneous delivery of luteolin: A comprehensive in-vitro and in-vivo evaluation

S Hatem, M El-Kayal - European Journal of Pharmaceutical Sciences, 2023 - Elsevier
Psoriasis is a prevalent laborious inflammation in skin with alternate phases of remission
and relapses. The current study sought to develop nanostructured lipid carriers (NLCs) …