There are a surprisingly large number of human natural killer (NK) cell deficiency states that
provide insight into the role of NK cells in defense against human infectious disease. Many …

When once your point of view is changed, the very thing ADCC mediated by NK cells is
initiated by engagement which was so damning becomes a clue to the truth. of low-affinity Fc …

In this study, we have used a newly generated monoclonal antibody (mAb C1. 7) to identify a
novel 38-kD signal-transducing surface molecule (p38) expressed by lymphocyte subsets …

VERY little is known about the receptors and target molecules involved in natural killer (NK)
cell activity. Here we present a model system in which interleukin-2-activated killing by NK …

Natural killer (NK) cells are named based on their natural cytotoxic activity against a variety
of target cells. However, the mechanisms by which sensitive targets activate killing have …

A new anti‐p58 monoclonal antibody (mAb), termed CH‐L, has been used to characterize a
minor subset of T lymphocytes co‐expressing p58 and CD3 molecules. In two‐color …

Natural killer cells are non-major histocompatibility complex-restricted large granular
lymphocytes that can recognize and destroy tumor cells without prior stimulation. A 150-kDa …

Receptors used by natural killer (NK) cells to mediate natural cytotoxicity are poorly defined,
although it is now clear that a number of adhesion molecules can serve this function. CD38 …

In the past year, significant strides have been made in understanding natural killing, the
process whereby natural killer cells lyse target cells. Recognition of susceptible targets and …

Cyclophilins (Cyps) belong to a group of proteins that have peptidyl-prolyl cis–trans
isomerase (PPIase) and molecular chaperone activities. Originally, Cyps were identified as …