Epithelial-to-mesenchymal transition (EMT) programs contribute to the acquisition of
invasive properties that are essential for metastasis. It is well established that EMT programs …

The evolution of established cancers is driven by selection of cells with enhanced fitness.
Subclonal mutations in numerous epigenetic regulator genes are common across cancer …

Hepatocellular carcinoma (HCC) is one of the most frequent forms of liver cancer, and
effective treatment methods are limited due to tumor heterogeneity. There is a great need for …

Primary aldosteronism (PA) is the most common form of endocrine hypertension and is
characterized by inappropriately elevated aldosterone production via a renin-independent …

Cervical cancer (CC) is a leading cause of cancer-related death in women. Limited studies
have investigated whether immune-related genes (IRGs) or tumor immune …

The transcriptome of prostate cancer is highly heterogeneous, with noncoding transcripts
being essential players. Long noncoding RNAs (lncRNAs) and circular RNAs (circRNAs) are …

Hepatocellular carcinoma (HCC) is the most common form of primary adult liver cancer. After
nearly a decade with sorafenib as the only approved treatment, multiple new agents have …

We propose a method for supervised learning with multiple sets of features (“views”). The
multiview problem is especially important in biology and medicine, where “-omics” data …

The canonical model of RB-mediated tumour suppression developed over the past 30 years
is based on the regulation of E2F transcription factors to restrict cell cycle progression …

A growing number of druggable targets and national initiatives for precision oncology
necessitate broad genomic profiling for many cancer patients. Whole exome sequencing …